Treating vitiligo at the angle of lips: A narrative review

Agrawal, Ishan; Kar, Basudeba; Singh, BhabaniS T P

doi:10.4103/jcas.jcas_10_22

J Cutan Aesthet Surg

2022

DOI: 10.4103/jcas.jcas_10_22

|View full text |Cite

Treating vitiligo at the angle of lips: A narrative review

Ishan Agrawal

Basudeba Kar

BhabaniS T P Singh

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2023

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

(1 citation statement)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This poor response is primarily due to the absence of hair follicles and a paucity of melanocyte reservoir. 4,5 Given this context, the intriguing aspect here lies in the high repigmentation rate observed in the lower face, especially considering the involvement of the lips. It would be interesting to know the specific repigmentation rates of the lips themselves, as this could provide valuable insights into the dynamics of vitiligo treatment outcomes in this challenging area.Other authors have also reported similar findings, emphasizing the variable response of different body sites.…”

mentioning

confidence: 99%

Deciphering differential response to NB‐UVB: The hair matters

Ahuja,

Gupta

2023

Acad Dermatol Venereol

View full text Add to dashboard Cite

Dear Editor, We read with interest the letter by Narayan et al. 1 on the variable response of NB-UVB phototherapy in different body sites in non-segmental vitiligo. This was a well-conducted multicentre study and the authors have delineated four body regions, that is face, torso and limbs, axillae and hands and feet, as distinct sites showing different rates of median repigmentation (76%, 40%, 27% and 4%, respectively).An important determinant of this differential treatment response emerges from the presence or absence of pigmented hair. Acral regions, characterized by significantly lower hair follicle density and inherently lower melanocyte density, are more resistant to phototherapy. 2 Consequently, differentiating body areas into glabrous versus hair-bearing sites assumes paramount significance when contemplating treatment outcomes in non-segmental vitiligo. Furthermore, consideration should be given to the presence or absence of leukotrichia, as pigmented hairs harbour a robust melanocyte reservoir, thereby increasing the likelihood of a favourable response to phototherapy. 3 The authors' observation regarding a significantly higher repigmentation rate, reaching approximately 80%, in the lower face region compared to the lower limbs (which achieved around 64% repigmentation) is quite noteworthy. It's important to note that the lips are part of the lower face, and this area is notorious for its generally poor response to both medical management and phototherapy. This poor response is primarily due to the absence of hair follicles and a paucity of melanocyte reservoir. 4,5 Given this context, the intriguing aspect here lies in the high repigmentation rate observed in the lower face, especially considering the involvement of the lips. It would be interesting to know the specific repigmentation rates of the lips themselves, as this could provide valuable insights into the dynamics of vitiligo treatment outcomes in this challenging area.Other authors have also reported similar findings, emphasizing the variable response of different body sites. In a systematic review, it was shown that the most responsive body site was the face and neck, with a notable repigmentation rate of 44.2%. This was followed by the trunk (26.1%), extremities (17.3%) and hands and feet (0%). However, these authors have also identified potential confounding factors, such as disease activity, autoimmune status, the extent of involved body surface area and the presence of poliosis, which could influence treatment outcomes. 6

show abstract

mentioning

confidence: 99%

Deciphering differential response to NB‐UVB: The hair matters

Ahuja,

Gupta

2023

Acad Dermatol Venereol

View full text Add to dashboard Cite

show abstract

308 nm excimer laser and tacrolimus ointment in the treatment of facial vitiligo: a systematic review and meta-analysis

Suo,

Zeng,

Meng

2024

Lasers Med Sci

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Treating vitiligo at the angle of lips: A narrative review

Cited by 2 publications

References 36 publications

Deciphering differential response to NB‐UVB: The hair matters

Deciphering differential response to NB‐UVB: The hair matters

308 nm excimer laser and tacrolimus ointment in the treatment of facial vitiligo: a systematic review and meta-analysis

Contact Info

Product

Resources

About