Treatment Adherence and Its Associated Factors in Patients with Type 2 Diabetes: Results from the Rio de Janeiro Type 2 Diabetes Cohort Study

Abstract

Objectives To investigate treatment adherence in patients with type 2 diabetes and to evaluate its associated factors. Methods The Summary of Diabetes Self-Care Activities (SDSCA) questionnaire was used to assess treatment adherence. Good adherence was defined as ≥5 days a week in each SDSCA item. Pain, emotional, and physical domains of the SF-36 quality of life questionnaire and the Canadian Occupational Performance Measure (COPM) were also evaluated. Multivariable logistic regressions explored the independent correlates of good general adherence and of specific items of the SDSCA (diet, exercise, and medications). Results Good adherence was 93.5% for medication use, 59.3% for foot care, 56.1% for blood glucose monitoring, 29.2% for diet, and 22.5% for exercise. Patients with general good adherence had lower BMI, better serum lipid profile, higher values of functional capacity, emotional and pain domains of SF-36, better occupational performance, and lower prevalence of pain or limitation in the upper and lower limbs than patients with worse adherence. The variables associated with good adherence were younger age, lower BMI, presence of macrovascular complications, better occupational performance and emotional domain of SF-36, and higher HDL cholesterol levels. The presence of pain/limitation in the upper limbs was associated with worse adherence. Good medication adherence was associated with longer diabetes duration, lower BMI, and lower HbA1c levels. Higher values of pain and emotional domains of the SF-36 and lower BMI were related to better exercise and diet adherence, while the presence of peripheral neuropathy and joint pain/limitation were associated with worse exercise adherence. Conclusions Emotional and physical performances are important determinants of good diabetic treatment adherence. Good adherence has beneficial impact on BMI, lipid, and glycemic control.

Non‐adherence to pharmacotherapy and its associated factors among patients with angina in Jordan

“…Consistent with the current study findings, Boratas & Kilic found a significant association between duration of illness and medication non‐adherence in patients with hypertension in Turkey . A study conducted by Marinho et al . has also found that increased duration of disease was associated with increased risk of non‐adherence to medications in patients with type 2 diabetes in Brazil.…”

“…Consistent with the current study findings, Boratas & Kilic found a significant association between duration of illness and medication non-adherence in patients with hypertension in Turkey. [28] A study conducted by Marinho et al [29] has also found that increased duration of disease was associated with increased risk of non-adherence to medications in patients with type 2 diabetes in Brazil. Another study reported that longer duration of disease was a predictor of medication non-adherence in patients with diabetes in Gaza, but this association was not statistically significant.…”

Diabetic Patients’ Quality of Life and Their Relationship in Compliance with Antidiabetic Treatment. Case Study of Patients in a Public Hospital in Greece

“…blood, self-care recommendations) and all dimensions of quality of life, as assessed by the SF-36 scale, but were not identified in the present study due to possible differences in the samples between the two studies. Similarly, previous research performed worldwide has shown that compliance with antidiabetic treatment is associated with increased levels of quality of life [22], [23]. However, the present study did not find any such associations.…”

The Association between Diabetes-Related Distress and Medication Adherence in Adult Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study

“…The prevalence of both chronic microvascular and acute complications of T2DM is much greater in patients with poor glycemic control and poor dietary quality [10,53,54]. Concerns about meeting dietary requirements and following treatment plans were also synonymous to the concept of diabetes distress in this study.…”