Treatment and labeling of silica sand for obtaining a prospective solid 99mTc radiotracer

Abstract

Pretreated silica sand labeling using varying concentrations of tin(II) fluoride and chloride as reducing agents and different times labeling was performed in order to develop a methodology for labeling silica sand with 99mTc for using as solid radiotracer. Influence of different sand pretreatment parameters on the sorption yield (Rret%) was statistically evaluated. The effectiveness of the methods used to reduce pertechnetate (99mTcO4−) by ascending paper chromatography was confirmed. Results show relatively high values of 99mTc sorption yields on silica sand. It was possible to establish a methodology for obtaining solid 99mTc labeled radiotracers in support of silica sand.