Treatment and Outcome of Recurrent Pelvic Chondrosarcoma

Weber, Kristy; Pring, Maya E.; Sim, Franklin H.

doi:10.1097/00003086-200204000-00004

Cited by 59 publications

(58 citation statements)

References 22 publications

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“…Part of the reason for this is that patients may survive a long time with disease and have multiple recurrences. Most patients (65%) had at least one additional local recurrence, which is consistent with the findings of Weber et al [18]. In our study, multiple local recurrences did not correlate with survival, and some patients lived many years with numerous local recurrences, but without metastasis.…”

Section: Discussionsupporting

confidence: 92%

“…Previous studies have been limited in scope and were focused on patients with low-grade chondrosarcoma [15] or pelvic disease [18]. We therefore (1) determined the survival of patients after local recurrence of chondrosarcoma in a broader group of patients; (2) determined the rate of further local recurrence; and (3) identified factors that might affect survival.…”

Section: Discussionmentioning

confidence: 99%

“…The prognosis for patients after local relapse is not well defined, and few reports [15,18] have studied the survival of patients after local recurrence. One study examined local recurrence of low-grade chondrosarcoma in the long bones and found local recurrence was associated with worse survival [15].…”

Section: Introductionmentioning

confidence: 99%

“…One study examined local recurrence of low-grade chondrosarcoma in the long bones and found local recurrence was associated with worse survival [15]. A study of local recurrence in the pelvis found a 71% rate of second local recurrence [18]. It should not be assumed local relapse has the same prognostic implication in chondrosarcoma as in osteosarcoma or Ewing's sarcoma.…”

Section: Introductionmentioning

confidence: 99%

“…One study of locally recurrent pelvic chondrosarcoma found 71% of patients have at least a second local recurrence, but only 24% of patients develop metastases [18]. This suggests, for a substantial number of patients, local recurrence can be a poor prognostic sign and can contribute directly to diminished rates of survival [2].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Sixty Percent 10-year Survival of Patients With Chondrosarcoma After Local Recurrence

Lin

Alfawareh

Takeuchi

et al. 2012

Clinical Orthopaedics &Amp; Related Research

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Background Chondrosarcoma is treated primarily by surgery. The prognosis of patients after local recurrence is not well defined. Both the survival of patients and the risk of further local relapse after surgical treatment of local recurrence have yet to be established. Questions/purposes We determined survival after local recurrence of chondrosarcoma, the rate of further local recurrences, and prognostic factors predicting survival. Patients and Methods We retrospectively reviewed 52 patients treated for locally recurrent conventional chondrosarcoma between 1975 and 2008. All patients had nonmetastatic disease at the time of diagnosis. There were 36 males and 16 females with a median age of 39 years (range, 16-79 years). We analyzed variables affecting overall and disease-free survival. The minimum followup was 12 months unless patients died of disease before 12 months (median, 68 months; range, 4-387 months).Results Thirty patients developed their first local recurrence in axial locations, while 22 developed recurrence in the appendicular skeleton. After local recurrence, overall survival was 74% at 5 years and 60% at 10 years. The mean number of local recurrences was three (range, 1-14).

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%