Treatment and rehabilitation of hydatidiform mole

Abstract

Methods: This is a prospective study conducted at a tertiary care centre in Department of pathology. Results: On PAP smear, majority (n ¼ 81, 54.7%) were of inflammatory smears. LSIL and HSIL were reported in 5.4% and 18.2% respectively. ASCUS accounts for 18.9% (n ¼ 28) whereas HGSI was seen in 2.7% of cases. On cervical biopsy, it was found that chronic cervicitis was dominant (n ¼ 106, 71.6%) followed by squamous cell carcinoma (n ¼ 17, 11.5%), Leiomyoma (n ¼ 7, 4.7%) and microinvasive adenocarcinoma (n ¼ 2, 2%) CIN, CIN2 and CIN3 accounts for 2%, 3.5% and 2% respectively. Incidence of cervical cancer was found higher in age group 41-61 years and with women having 2 children (19.5%) and have repeated abortion or miscarriage Chronic cervicitis was predominant in nulliparous women (n ¼ 22, 73.3%) and cervical neoplasia and carcinoma occupies 13.3% and 26.5% respectively. 33.1% had normal menstrual history while 18.2% and 2.7% has irregular menses and menorrhagia respectively. Menopause accounts for 12.2%. Frequency of carcinoma was seen to be higher in women having irregular menses (43.75%). 10.8% cases diagnosed on cytology turned out to be malignant on biopsy. Cervical abnormalities was found to be positively correlated with age (r ¼ 0.032, p < 0.05) and menstrual abnormalities (r ¼ 0.212, p < 0.05) respectively. Conclusions: Mostly women at older ages and have multiple births are considered to be prone to cervical neoplasia and carcinoma but our study concluded that even nulliparous women at their younger ages are also at high risk and menstrual abnormalities may also be a factor for cervical abnormalities.