Treatment and survival outcomes of ceruminous carcinomas of the external auditory canal: a SEER database analysis and literature review

Primary mucoepidermoid carcinoma of the external auditory canal with a CRTC1::MAML2 fusion: A case report and a review of literature

“…They reported an additional literature review of eight cases where the local recurrence, disease-specific death, and OS were 38%, 18%, and 86%, respectively; however, some of the tumors analyzed were termed "ceruminous adenocarcinomas" and it is unclear whether they represent true mucoepidermoid carcinomas or another adenocarcinoma subtype. 15 Histopathologically, the microscopic findings of cMEC are similar to those in the salivary glands. It consists of a dermal-based proliferation of mucous, epidermoid, intermediate cells, and occasionally clear cells with variable duct, cyst, and papillary formation.…”

“…It can present as an asymptomatic mass with or without ear fullness, otalgia, dizziness, tinnitus, and/or otorrhea 8–11,14 . A recent study reported only four cases in a cohort of 135 individuals with ceruminous carcinomas of the external auditory canal 15 . One patient died as a result of the tumor and one was alive at the conclusion of the study.…”

“…One patient died as a result of the tumor and one was alive at the conclusion of the study. They reported an additional literature review of eight cases where the local recurrence, disease‐specific death, and OS were 38%, 18%, and 86%, respectively; however, some of the tumors analyzed were termed “ceruminous adenocarcinomas” and it is unclear whether they represent true mucoepidermoid carcinomas or another adenocarcinoma subtype 15 …”