Treatment compliance in children and adults with Cystic Fibrosis

Llorente, Rosa Patricia Arias; García, Carlos Bousoño; Martín, Juan José Díaz

doi:10.1016/j.jcf.2008.01.003

Cited by 134 publications

(122 citation statements)

References 23 publications

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“…3,10,11,20,[22][23][24][25][27][28][29][31][32][33][34][35][36][37][38][39] Eighteen papers were of low quality, and 2 were of moderate quality. The categories of medications are summarized below (Table 3).…”

Section: Medicationmentioning

confidence: 99%

Adherence of Subjects With Cystic Fibrosis to Their Home Program: A Systematic Review

O'Donohoe

Fullen

2014

Respir Care

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BACKGROUND: The management of cystic fibrosis (CF) includes adherence to a home management program (airway clearance, medication, nutritional advice, and exercise). This has led to an increase in life expectancy, although the benefits depend greatly on a patient's level of adherence to daily treatments at home. To date, no systematic review has established adherence rates to all World Health Organization guidelines in the home setting; hence, this review was undertaken. METHODS: The review comprised 3 phases. A methodological assessment of databases (Embase, CINAHL, PsychINFO, PEDro, PubMed, Cochrane Central Register of Controlled Trials) identified potentially relevant papers. These papers were screened for inclusion criteria by 2 independent reviewers, data were extracted, and the internal validity was rated using a valid and reliable scale. Results were categorized into 4 themes: medication, nutrition, airway clearance techniques, and exercise. RESULTS: The search generated a total of 26 papers, 24 of which were rated as being poor quality. Adherence to a treatment program for CF patients is generally low (from 22% for nutritional guidelines to 130% for oral antibiotics), and it varies greatly depending on the type of treatment and the method of assessment employed (objective tool vs self-reported questionnaires). CONCLUSIONS: Consensus on how to measure adherence is lacking, and the quality of studies addressing adherence in this population is generally poor. Overall, studies using self-reported measures yielded higher adherence scores than those that used objective measures, suggesting that current efforts to improve methods of adherence are appropriate. The prevalence of non-adherence remains unclear due to these limitations.

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Section: Medicationmentioning

confidence: 99%

Adherence of Subjects With Cystic Fibrosis to Their Home Program: A Systematic Review

O'Donohoe

Fullen

2014

Respir Care

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“…Whilst non-adherence to CF treatments is well-reported and linked to negative health outcomes [5][6][7][8][9] , adherence to IPC recommendations is less well-understood. Patient rates of avoiding contact with other people with CF are reported to be low (21%-27%), particularly in young adults 10,11 .…”

Section: Introductionmentioning

confidence: 99%

Adherence to infection prevention and control guidelines: A vignette-based study of decision-making and risk-taking in young adults with cystic fibrosis

Bowmer

Latchford

Duff

et al. 2017

Journal of Cystic Fibrosis

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“…However, treatment remains complex and time-consuming, often interfering with activities of daily living (90)(91)(92). Adherence is superior to medication perceived as more important or more likely to improve quality of life (74,93). Therefore, it is not surprising that adherence to digestive and respiratory medications is much better than the adherence to physiotherapy or nutritional supplements.…”

Section: Cf and Nonadherencementioning

confidence: 99%

“…Therefore, it is not surprising that adherence to digestive and respiratory medications is much better than the adherence to physiotherapy or nutritional supplements. Age and severity of disease have both negative and positive effects on adherence (74,93). Living with CF appears to have a greater emotional impact on adolescent girls than boys (75).…”

Section: Cf and Nonadherencementioning

confidence: 99%