Treatment effect modifiers for the patient education programme for Parkinson’s disease

Abstract

A potential predictor of treatment benefit was found for caregivers of PD patients with better cognitive functioning. This study did not find treatment effect modifiers for PD patients: demographics, disease stage and time of diagnosis, cognitive functioning, level of baseline psychosocial burden, participating with or without a caregiver, and caregiver changes did not influence treatment outcome. The PEPP seems suitable for the majority of patients.

Structured Care and Self-Management Education for Persons with Parkinson’s Disease: Why the First Does Not Go without the Second—Systematic Review, Experiences and Implementation Concepts from Sweden and Germany

“…Both qualitative (3, 13%) [ 23 , 27 , 38 ] and (9, 39%) quantitative studies have been performed for evaluation of PD-related self-management programs [ 21 , 22 , 26 , 30 , 31 , 32 , 34 , 39 , 40 ]. Additionally, 8 (35%) studies combined quantitative data collection with qualitative descriptive aspects for program evaluation [ 24 , 28 , 29 , 36 , 41 , 42 , 43 , 44 ].…”

Effects of self‐management education for persons with Parkinson's disease and their care partners: A qualitative observational study in clinical care

“…Measuring the long‐term effects and efficacy of educational interventions for PwPD has proved to be difficult. Studies using traditional outcome measures such as HRQoL or depression scales have shown short‐term improvements but have failed to show long‐term effects with repeated measures 6 to 12 months post intervention (A'Campo et al, 2012; Nelson, Wong, & Lai, 2011). Failure to measure long‐term effects could have several reasons.…”

“…This study is the first to our knowledge to study effects and outcomes of a self‐management educational program for PwPD through observations in a clinical practice setting. Previous studies evaluating outcomes of self‐management programs for PwPD either report the participant's view and experience through qualitative interviews or evaluate outcomes using scales measuring, for example, quality of life, mood and everyday functioning (A'Campo et al, 2011; Baudet et al, 2015; A'Campo, Spliethoff‐Kamminga, et al, 2010; A'Campo, Spliethoff‐Kamminga, Stijnen, & Roos, 2012; A'Campo, Wekking, et al, 2010; Hellqvist et al, 2018; Macht et al, 2007).…”

Enhanced self-efficacy after a self-management programme in pituitary disease: a randomized controlled trial

“…The SMI was based on the standardized Patient (and Partner) Education Programme initially developed for Parkinson's disease (PEPP), and evaluated in seven European countries (11,12) including the Netherlands (13,14,15), and is currently operational in patient care. The programme was then adapted for Huntington's disease (PEP-HD) (16) and was further developed and clinically tested in patients with chronic disease with psychiatric comorbidity (17).…”