Treatment effect of TUSPLV on recurrent varicocele

Yan, Tianzhong; Wu, Xiaoqiang; Wang, Zhiwei

doi:10.3892/etm.2016.3931

Cited by 6 publications

(10 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The outcome measures were spontaneous pregnancy, improvement in sperm parameters and complications (recurrence, hydrocele, testicular atrophy and infection–haematoma). As shown in Table , of the studies reporting treatment of recurrent varicocele, 21 (612 subjects) met the inclusion criterion, reporting at least one of the post‐treatment sperm parameters, spontaneous pregnancy and complication rates in adults and adolescents who underwent treatment for recurrent varicocele (Çayan & Akbay, ; Chawla et al, ; Chen, ; Çift & Yucel, ; Feneley et al, ; Flati et al, ; Glassberg et al, ; Grober et al, ; Guevara et al, ; Jargiello et al, ; Kaufman et al, ; Kenawi, ; Kim et al, ; Lund & Jensen, ; Madjar et al, ; Mazzoni et al, ; Moon et al, ; Niedzielski et al, ; Punekar et al, ; Sze et al, ; Yan et al, ). Interventions were divided into surgical (open or laparoscopic) and radiological (sclerotherapy or embolisation) groups.…”

Section: Methodsmentioning

confidence: 99%

“…Recurrent varicoceles can be treated via open redo surgical, radiologic and laparoscopic approaches (Çayan & Akbay, ; Chawla, Kulkarni, Kamal, & Zini, ; Chen, ; Çift & Yucel, ; Feneley, Pal, Nockler, & Hendry, ; Flati et al, ; Glassberg et al, ; Grober, Chan, Zini, & Goldstein, ; Guevara, El‐Hilal, & Darcy, ; Jargiello et al, ; Kaufman et al, ; Kenawi, ; Kim et al, ; Lund & Jensen, ; Madjar, Moskovitz, Issaq, Weinberger, & Nativ, ; Mazzoni, Minucci, & Gentile, ; Moon, Cho, Kim, Park, & Park, ; Niedzielski & Paduch, ; Punekar, Prem, Ridhorkar, Deshmukh, & Kelkar, ; Sze et al, ; Yan, Wu, & Wang, ). Recurrent varicoceles have been previously treated with radiological methods, because of redo surgical complications, including testicular atrophy, hydrocele and nerve injury (Feneley et al, ; Guevara et al, ; Jargiello et al, ; Kaufman et al, ; Kim et al, ; Mazzoni et al, ; Punekar et al, ; Sze et al, ).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Systematic review of treatment methods for recurrent varicoceles to compare post‐treatment sperm parameters, pregnancy and complication rates

et al. 2019

View full text Add to dashboard Cite

We aimed to define which method would be the best for the treatment of recurrent varicoceles. We analysed 21 studies to compare post‐treatment improvement in semen parameters, spontaneous pregnancy and complication rates between the treatment methods. Overall spontaneous pregnancy rate was significantly higher in the surgical methods (44.3%) than in the radiological interventions (17.9%; p = .007). Post‐treatment improvement rates in sperm parameters were significantly higher in the open surgical methods (77.5%) than in the radiological interventions (62.5%; p = .032). Post‐treatment recurrence rates were 3.8% in the open surgical methods, 17.6% in the laparoscopic surgery and 3.3% in the radiological interventions. However, technical failure rate was 11.8% in the radiologic interventions. To analyse open surgical methods, recurrence rate was 0.6% in the microsurgical methods and 19% in the macroscopic methods, revealing significant difference (p < .001). Post‐treatment testicular atrophy rate was significantly higher in the laparoscopic surgery (2.9%) than in the open surgery (0.3%; p = .033). In conclusion, surgical methods have higher pregnancy rates and higher improvement rate in sperm parameters than radiological interventions for the treatment of recurrent varicocele. Microsurgical redo varicocelectomy has lower recurrence and testicular atrophy rates than macroscopic varicocelectomy series. Therefore, patients with recurrent varicoceles should be informed based on these findings.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Systematic review of treatment methods for recurrent varicoceles to compare post‐treatment sperm parameters, pregnancy and complication rates

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Hydrocele formation, testicular artery injury, vascular and abdominal organ injury, and infection were reported in the retroperitoneal series with an incidence of 10%, 3%, 10%, and 6% respectively (Yan et al, 2017). Whereas in the laparoscopic technique the risks of Hydrocele formation, testicular artery injury, vascular and abdominal organ injury, and infection was 3% for all (Yan et al, 2017).…”

Section: Resultsmentioning

confidence: 99%

“…Of the seven articles, four evaluated the outcome of micro surgical technique (Cayan & Akbay, 2018;Chen, 2014;Grober et al, 2004;Madjar et al, 1998), two the radiological approach (Punekar et al, 1996;Sze et al, 2008) and one looked for both open retroperitoneal and laparoscopic surgery (Yan et al, 2017). Quality assessment revealed that two studies were of good quality (9 stars) (Cayan & Akbay, 2018;Chen, 2014), while the remaining studies were of fair quality (5-6 stars).…”

Section: Meta-analysismentioning

confidence: 99%

Effect of redo varicocelectomy on semen parameters and pregnancy outcome: An original report and meta‐analysis

et al. 2022

View full text Add to dashboard Cite

Recurrence following varicocelectomy is an important cause of treatment failure and persistence of subnormal semen parameters. This original study was combined with a systemic review and meta‐analysis aiming to evaluate the efficacy of redo varicocelectomy on male fertility potential and pregnancy outcome. The retrospective study included 32 patients who underwent microsurgical subinguinal varicocelectomy for patients with recurrent varicocele. Changes in semen parameters and hormone profiles before and after surgery were compared. The literature review followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses and included seven articles in addition to our original report. Results of the original study revealed statistically significant improvements in sperm concentration, progressive motility, total motile sperm count and normal morphology following redo varicocelectomy. The meta‐analysis results echoed those reported in our original study and depicted significant improvements in sperm concentration (mean difference [MD] = +20.281 million/ml, p < 0.001), total motility (MD = +9.659%, p = 0.001), total motile sperm count (MD = +23.258 million sperm, p < 0.001) and normal morphology (MD = +4.460%, p < 0.001). Overall pregnancy outcome was reported in seven studies with a rate of 34.6%. No significant changes were noted in any of the collected hormone results both in this original report and in the meta‐analysis. In conclusion, redo varicocelectomy has a beneficial role on male fertility potential and can be offered for men with recurrent varicocele as directed by their individual clinical condition.

show abstract

“…Overlooking small internal spermatic veins, especially during macroscopic surgery which later become dilated, are the disadvantages of macroscopic surgery [11] , it is still controversial which treatment is to be preferred for recurrent varicocele. Although microsurgery, embolization, and laparoscopic surgical methods are preferable methods for varicocele recurrence, varicocelectomy with microsurgical method is the recommended treatment modality due to its lesser number of side effects and complications [12][13][14][15][16] .…”

Section: Discussionmentioning

confidence: 99%

Microsurgical subinguinal varicocelectomy in patients with recurrent or persistent varicocele

Sobay¹

2018

Haydarpasa Numune Med J

View full text Add to dashboard Cite

Introduction:Varicocele may be treated with many different modalities including radiological and surgical approaches but what is the best treatment remains controversial. The recurrence rate following varicocele repair is up to 45%. The aim of this study is to investigate the efficacy of microsurgical varicocelectomy in varicocele recurrence. Methods: In our clinic, 32 men who treated with persistent or recurrent varicocele were evaluated retrospectively. All patients were treated with artery and lymphatic sparing subinguinal microsurgical technique. Age, pre-operative and post-operative semen parameters, serum testosterone levels, post-operative pregnancy rates, testicular volumes, and complications were recorded and analyzed. Results: Postoperatively, mean serum testosterone levels increased. Median sperm concentrations and motility rates also increased. With a minimum 6-month follow-up, the overall pregnancy rate was 37.5% (n=12) including 18.7% (n=6) of pregnancies achieved through natural intercourse, 9.3% (n=3) of them with IVF/intracytoplasmic sperm injection, and 9.3% (n=3) with intrauterine insemination. No complications such as hydrocele, hematoma, and wound infection were observed during the follow-up period. Discussion and Conclusion: In this study, treatment of recurrent varicocele with subinguinal microsurgical technique seems to be effective method with improving semen parameters and without a significant risk of post-operative complications.

show abstract

Treatment effect of TUSPLV on recurrent varicocele

Cited by 6 publications

References 17 publications

Systematic review of treatment methods for recurrent varicoceles to compare post‐treatment sperm parameters, pregnancy and complication rates

Systematic review of treatment methods for recurrent varicoceles to compare post‐treatment sperm parameters, pregnancy and complication rates

Effect of redo varicocelectomy on semen parameters and pregnancy outcome: An original report and meta‐analysis

Microsurgical subinguinal varicocelectomy in patients with recurrent or persistent varicocele

Contact Info

Product

Resources

About