Treatment efficacy and prognosis of pulmonary metastasizing ameloblastoma: a systematic review

Yang, Xu; Zhou, Kefei; Tao, Yubing; Ge, Shengyou; Shang, Weiwei; Song, Kejuan

doi:10.1016/j.ijom.2021.07.016

Cited by 3 publications

(1 citation statement)

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“…It is particularly rare type of ameloblastoma and despite its affiliation with benign tumors, it metastasizes to distant sites and makes treatment unpredictable with a high recurrence rate [20]. It is most commonly found in lungs, but other sites, such as brain and kidneys have also been reported [21].…”

Section: Classificationmentioning

confidence: 99%

Perspective Chapter: Ameloblastoma – Present and Future Concepts of Managing

Gabrić¹,

Bjelica²,

Sušić³

et al. 2023

Bone Tumours - A Comprehensive Review of Selected Topics

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Ameloblastoma is a benign odontogenic tumor of epithelial origin with locally aggressive behavior. It affects a broad age range of patients and it is most commonly found in the mandible, especially posterior area. The majority of ameloblastomas are conventional (multicystic), which are more difficult to eradicate than the unicystic or peripheral types. Although most of ameloblastoma cases can be treated predictably with radical surgical treatment, the management of recurrent and metastasizing ameloblastomas remains a major challenge. Surgical treatment is standard, but the extent of resection is controversial. Radical resection with segmental and marginal mandibulectomy or curettage and enucleation with better quality of life, but with higher recurrence rate. Besides the conventional surgical treatment, novel therapy options like neoadjuvant molecular targeted therapy and decompression in young patients could make a significant improvement in the management of the disease. The aim of this chapter was to determine the present and future concepts of treatment and discuss significant factors responsible for recurrence.

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Section: Classificationmentioning

confidence: 99%