Treatment for and Clinical Characteristics of Granulomatous Mastitis

Sheybani, Fereshte; Sarvghad, MohammadReza; Naderi, HamidReza; Gharib, Masoumeh

doi:10.1097/aog.0000000000000734

Cited by 122 publications

(131 citation statements)

References 31 publications

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“…Since GLM was first described as a separate type of breast disease in 1972 [1], many studies, especially in the last decade, have focused on clinical presentation and treatment options [7,8]. However, so far, the etiology and optimal treatment of GLM are still unclear.…”

Section: Discussionmentioning

confidence: 99%

Granulomatous Lobular Mastitis: Antituberculous Treatment and Outcome in 22 Patients

et al. 2018

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Background: Granulomatous lobular mastitis (GLM) is a rare chronic inflammatory condition of the breast. The purpose of this study was to describe antituberculous treatment of GLM and the long-term follow-up outcome. Methods: This retrospective study included 22 patients who had been histopathologically diagnosed with GLM at the Second Hospital of Shandong University from January 2011 to March 2015. Clinical characteristics, ultrasonography and mammography findings, laboratory tests, treatment regimens, follow-up information, and recurrences were recorded. Results: All patients were female with a median age of 29 (range 23-44) years. The most common symptom was a breast mass with or without pain. Large irregular hypoechoic masses could be found in the breast ultrasounds of 13 patients. All patients received triple antituberculous therapy. During a median follow-up period of 40 months, 3 patients were lost to follow-up; of the remaining 19 patients, 18 achieved clinical complete remission and no recurrences were observed. Conclusion: GLM is an unusual benign breast condition that mimics breast carcinoma in its clinical and imaging presentation. Antituberculous therapy seems to be an effective alternative option in the treatment of GLM.

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Section: Discussionmentioning

confidence: 99%

Granulomatous Lobular Mastitis: Antituberculous Treatment and Outcome in 22 Patients

et al. 2018

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“…Mastitis is usually seen in lactating women, but the presence in a nonlactating woman should spur evaluation for an inflammatory carcinoma, newly onset diabetes, infection with Mycobacterium tuberculosis, and other idiopathic causes. 17 Lactational mastitis is seen in approximately 2% -3% of lactating women 18 and breast abscess may develop in 5% -11% of women with mastitis. 19 …”

Section: Histopathological Findings Of Breast Diseasesmentioning

confidence: 99%

Clinical and Histological Evaluation of Patients With Breast Diseases

Chakkarapani¹,

Das²,

Dhanajayan³

2018

jemds

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BACKGROUND Breast pathologies being benign and malignant with varying treatment options remain a challenge for the surgeons. Also, the prognosis of the breast disease varies from one condition to the other. With this varying treatment options and prognosis, breast diseases especially breast carcinomas add burden not only to the health care sector but also to the patient in economic terms also. Hence, this study was planned to know the clinical profile of breast diseases among females more than 15 years of age. MATERIALS AND METHODSData was a descriptive study collected from hundred female patients above 15 yrs. of age who presented with breast lump, pain in the breast and nipple discharge and willing to undergo histopathology examination/ FNAC and treatment for their breast disease in outpatient and inpatient surgery department in

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“…Immunomodulators such as Azathiprine and Methotrexate as well as surgery have also been used in patients with more refractory cases. [1,2] Recurrences can happen in all treatment modalities.…”

Section: Introductionmentioning

confidence: 99%

“…[2] IGM classically presents as a unilateral painful breast mass in women who are 30-40 years of age. [1] When first encountered, IGM may mimic infectious mastitis or malignancy. Correct diagnosis depends on histopathologic findings of non-caeseating granulomas around the breast lobules.…”

Section: Introductionmentioning

confidence: 99%

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The role of dapsone in refractory idiopathic granulomatous mastitis

Pelleg

Varadaraju

Datta

2017

CRIM

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Idiopathic Granulomatous Mastitis (IGM) is a benign inflammatory breast disease. A definite etiology of IGM is still unknown. IGM classically presents as an unilateral, painful breast mass in women who are 30-40 years of age. Consensus treatment guidelines do not exist for the management of IGM. In this case report, we present a patient with IGM who was refractory to Prednisone and started on Dapsone as an alternative treatment. This case report highlights the use of Dapsone and the need for further research of IGM treatment modalities.

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Treatment for and Clinical Characteristics of Granulomatous Mastitis

Abstract: Idiopathic granulomatous mastitis is a distinct benign breast condition of unknown etiology but several triggers are suspected, including inflammatory, infectious, and hormonal factors. Corticosteroids and MTX, with or without surgery, are the treatment of choice in these patients.

Cited by 122 publications

References 31 publications

Granulomatous Lobular Mastitis: Antituberculous Treatment and Outcome in 22 Patients

Granulomatous Lobular Mastitis: Antituberculous Treatment and Outcome in 22 Patients

Clinical and Histological Evaluation of Patients With Breast Diseases

The role of dapsone in refractory idiopathic granulomatous mastitis

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