Treatment for superficial thrombophlebitis of the leg

Nisio, Marcello Di; Wichers, Iris

doi:10.1002/14651858.cd004982.pub4

Cited by 26 publications

(25 citation statements)

References 39 publications

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“…While strategies for the treatment of lower limb SVT are still debated [4,17,[22][23][24], this study provides useful information for future research on the management of this disease and its potential impact in terms of health care resource utilization and costs. This impact might call for implementing preventive strategies, for example, against varicose veins, which constitute the main risk factor for this disease.…”

Section: Discussionmentioning

confidence: 99%

Annual diagnosis rate of superficial vein thrombosis of the lower limbs: the STEPH community‐based study

Frappé

Buchmüller-Cordier

Bertoletti

et al. 2014

Journal of Thrombosis and Haemostasis

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Summary Background The incidence of superficial vein thrombosis (SVT) in the general adult population remains unknown. Objectives To assess the annual diagnosis rate of symptomatic, objectively confirmed lower limb SVT, associated or not with concomitant deep vein thrombosis and/or symptomatic pulmonary embolism. Methods/patients We conducted, from November 14, 2011, to November 13, 2012, a multicenter, community‐based study in the Saint‐Etienne urban area, France, representing a population of 265 687 adult residents (according to the 2009 census). All 248 general practitioners located within the area were asked to refer any patient with clinically suspected lower limb acute SVT to a vascular physician for systematic compression ultrasonography. All 28 vascular physicians located within the area participated in the study. The annual diagnosis rate, with the corresponding 95% confidence interval (CI), was calculated as the number of patients with symptomatic, objectively confirmed SVT divided by the number of person‐years at risk defined by population data of the area. All venous thromboembolic events were validated by an independent central adjudication committee. Results Overall, 171 patients with symptomatic, confirmed SVT were reported. The annual diagnosis rate was 0.64% (95% CI, 0.55%–0.74%), was higher in women, and increased with advancing age regardless of gender. Concomitant deep vein thrombosis (20 proximal) was observed in 42 patients (24.6% [95% CI, 18.3%–31.7%]), and concomitant symptomatic pulmonary embolism was observed in eight patients (4.7% [95% CI, 2.0%–9.0%]). Conclusions This first community‐based study showed that symptomatic SVT with confirmed diagnosis is a relatively common disease frequently associated with thromboembolic events in the deep venous system.

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Section: Discussionmentioning

confidence: 99%

Annual diagnosis rate of superficial vein thrombosis of the lower limbs: the STEPH community‐based study

Frappé

Buchmüller-Cordier

Bertoletti

et al. 2014

Journal of Thrombosis and Haemostasis

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“…1 In the past it was viewed as a benign, self-limiting disorder. However, in recent years it has been shown that individuals with SVT have a fourfold to sixfold higher risk of venous thrombosis than individuals without SVT.…”

Section: Introductionmentioning

confidence: 99%

The risk of venous thrombosis in individuals with a history of superficial vein thrombosis and acquired venous thrombotic risk factors

Roach¹,

Lijfering²,

Vlieg³

et al. 2013

Blood

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“…Superficial vein thrombosis (SVT) of the lower limbs is a frequent pathologic occurrence, with a prevalence estimated to be greater than that of deep vein thrombosis (DVT) and pulmonary embolism (PE) [1,2]. There is currently no consensus on the management strategy for SVT, and the treatment recommendations provided in the most recent American College of Chest Physicians guidelines (9th edn) have a low grade (2B) [3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Superficial vein thrombosis and recurrent venous thromboembolism: a pooled analysis of two observational studies

Galanaud

Bosson

Genty

et al. 2012

Journal of Thrombosis and Haemostasis

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Summary. Background: The management strategies for symptomatic isolated superficial vein thrombosis (SVT) (without concomitant deep vein thrombosis [DVT] or pulmonary embolism [PE]) have yet to achieve widespread consensus. Concerns have been raised regarding the usefulness of prescribing anticoagulant treatments to all patients with isolated SVT. Determining the isolated SVT subgroups who have the highest risks of venous thromboembolism (VTE) recurrence (composite of DVT, PE, and new SVT) may facilitate the identification of patients who are likely to benefit from anticoagulant treatment. Design and methods: We performed a pooled analysis on individual data from two observational, multicenter, prospective studies, to determine predictors for VTE recurrence and their impact in an unselected population of symptomatic isolated SVT patients. Results: One thousand and seventy‐four cases of symptomatic isolated SVT were followed up at 3 months. VTE recurrence was observed in 3.9% of the patients; 16.2% of the patients did not receive anticoagulants, and 0.6% experienced a VTE recurrence. Cancer, personal history of VTE and saphenofemoral/popliteal involvement significantly increased the risk of subsequent VTE or DVT/PE in univariate analyses. Only male sex significantly increased the risk of VTE or DVT/PE recurrence in multivariate analyses. Twelve per cent of the patients had cancer or saphenofemoral junction involvement, and were at higher risk of DVT/PE recurrence than patients without those characteristics (4.7% vs. 1.9%, P = 0.06). Conclusions: In patients with symptomatic SVT, only male sex significantly and independently increased the risk of VTE recurrence. Cancer or saphenofemoral junction involvement defined a population at high risk for deep VTE recurrence. Some SVTs might be safely managed without anticoagulants.

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Treatment for superficial thrombophlebitis of the leg

Cited by 26 publications

References 39 publications

Annual diagnosis rate of superficial vein thrombosis of the lower limbs: the STEPH community‐based study

Annual diagnosis rate of superficial vein thrombosis of the lower limbs: the STEPH community‐based study

The risk of venous thrombosis in individuals with a history of superficial vein thrombosis and acquired venous thrombotic risk factors

Superficial vein thrombosis and recurrent venous thromboembolism: a pooled analysis of two observational studies

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