Treatment of accidental intakes of plutonium and americium: Guidance notes

Ménétrier, Florence; Grappin, L.; Raynaud, Paul; Courtay, C.; Wood, R.G.; Joussineau, Siegfried; List, V.; Stradling, G.N.; Taylor, David; Berard, P.; Morcillo, Miguel A.; Rencová, J.

doi:10.1016/j.apradiso.2005.01.005

Cited by 65 publications

(46 citation statements)

References 9 publications

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“…A promptly administered DTPA aerosol would have the advantage that plutonium would be chelated in the respiratory tract, thus minimizing subsequent deposition in systemic tissues (2). Moreover, combined treatment involving early inhalation of DTPA followed by repeated intravenous injections is likely to be the most effective treatment method (6).…”

Section: Discussionmentioning

confidence: 99%

“…Guildford, Surrey, UK) ( Figure 2) method was developed, which enables rapid administration of spinhaler-generated aerosol of DTPA to contaminated personnel (2). These capsules of DTPA powder, which are from the Central Pharmacy of the French Army, cannot be distributed outside France, therefore, we prepared a portable ultrasonic mesh nebulizer ( Figure 3) that is small enough to carry on one's person in the radiation controlled area.…”

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confidence: 99%

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Diethylene-Triamine-Penta-Acetate Administration Protocol for Radiological Emergency Medicine in Nuclear Fuel Reprocessing Plants

Jin¹

2008

Hemoglobin

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Inhalation therapy of diethylene-triamine-penta-acetate (DTPA) should be initiated immediately to workers who have significant incorporation of plutonium, americium or curium in the nuclear fuel reprocessing plant. A newly designed electric mesh nebulizer is a small battery-operated passive vibrating mesh device, in which vibrations in an ultrasonic horn are used to force drug solution through a mesh of micron-sized holes. This nebulizer enables DTPA administration at an early stage in the event of a radiation emergency from contamination from the above radioactive metals.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

Diethylene-Triamine-Penta-Acetate Administration Protocol for Radiological Emergency Medicine in Nuclear Fuel Reprocessing Plants

Jin¹

2008

Hemoglobin

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“…Sb, Te, Mo, Sr and Pu are of intermediate importance [45]. Although Te, Mo and Pu have a small impact from the viewpoint of external exposure [27], they are important because Te and Mo are reported to form compounds with Cs, such as Cs 2 Te and Cs 2 MoO 4 [23,36], and Pu results in significant internal exposure [48]. Table 2.…”

Section: Priority Of Elements To Be Investigatedmentioning

confidence: 98%

Research Program for the Evaluation of Fission Product and Actinide Release Behaviour, Focusing on their Chemical Forms

et al. 2015

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We have launched a new research program for evaluation of fission product and actinide release behaviour under severe accident conditions, focusing on their chemical forms. In this research program, the fission product and actinide release models incorporated in the severe accident analysis code will be improved by implementing effects of chemical forms that are to be obtained by an experimental investigation on the fission product and actinide release behaviour from irradiated fuels. A novel insitu measurement method of chemical forms of fission products and actinides just after their release as well as an off-line analysis method will be employed as the experimental means for evaluating the chemical forms at the release and their stability after release.

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“…Plusieurs guides ont été mis à jour pour proposer des protocoles de traitements optimisés, en termes de décorporation, tenant compte de l'évolution des connaissances scientifiques et du retour d'expérience (Bhattacharyya et al, 1992 ;Hengé-Napoli et al, 2000 ;Ménétrier et al, 2005).…”

Section: Introductionunclassified