Cutis 2023
DOI: 10.12788/cutis.0767
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Treatment of Angiosarcoma of the Head and Neck: A Systematic Review

Abstract: Primary cutaneous angiosarcoma (cAS) of the head and neck is a rare sarcoma with a poor prognosis and limited treatment options. We conducted a systematic review of treatments used for head and neck cAS and determined the treatment modalities that offer the longest mean overall survival (OS). Forty publications totaling 1295 patients were included. Both surgical and nonsurgical modalities have shown potential efficacy in the treatment of cAS; however, limited data preclude definitive recommendations. Multidisc… Show more

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“…Most patients die within one year of diagnosis. 4 Primary gastrointestinal angiosarcoma is even rarer, and most patients have a survival period of only a few months after diagnosis. Most of them die due to multiple organ failure caused by extensive metastasis of the tumor in the late stage.…”
Section: Introductionmentioning
confidence: 99%
“…Most patients die within one year of diagnosis. 4 Primary gastrointestinal angiosarcoma is even rarer, and most patients have a survival period of only a few months after diagnosis. Most of them die due to multiple organ failure caused by extensive metastasis of the tumor in the late stage.…”
Section: Introductionmentioning
confidence: 99%