2000
DOI: 10.1002/1096-9101(2000)27:3<206::aid-lsm2>3.0.co;2-1
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Treatment of atrophoderma of Pasini and Pierini-associated hyperpigmentation with the Q-switched alexandrite laser: A clinical, histologic, and ultrastructural appraisal

Abstract: Treatment of APP with the Q-switched alexandrite laser results in clinical improvement. Electron microscopic evaluation suggests that the mechanism may be a reduction in the number, size, and volume of larger melanosomes as well as a decrement in melanin granule number and size.

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Cited by 22 publications
(11 citation statements)
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“…After three exposures, a clear clinical improvement was observed, as a 50% diminution in hyperpigmentation was obtained. No adverse reactions were reported during the treatment cycle [ 63 ].…”
Section: Resultsmentioning
confidence: 99%
“…After three exposures, a clear clinical improvement was observed, as a 50% diminution in hyperpigmentation was obtained. No adverse reactions were reported during the treatment cycle [ 63 ].…”
Section: Resultsmentioning
confidence: 99%
“…Systemic steroids, antimalarials, d-penicillamine, and phototherapy have been reported to be effective in some cases. Q-switched alexandrite laser has found to be effective in diminishing the hyperpigmentation (9).…”
Section: Discussionmentioning
confidence: 99%
“…Topical calcineurin inhibitors were found to have variable responses . Q‐switched alexandrite laser has also resulted in some clinical improvement of hyperpigmented lesions …”
Section: Discussionmentioning
confidence: 99%