Treatment of atrophoderma of Pasini and Pierini‐associated hyperpigmentation with the Q‐switched alexandrite laser: A clinical, histologic, and ultrastructural appraisal

Arpey, Christopher J.; Patel, Dipa S.; Stone, Mary Seabury; Qiang‐Shao, Jian; Moore, Kenneth C.

doi:10.1002/1096-9101(2000)27:3<206::aid-lsm2>3.3.co;2-t

Cited by 4 publications

(5 citation statements)

References 12 publications

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“…16 Q-switched alexandrite laser has also resulted in some clinical improvement of hyperpigmented lesions. 17 The differential diagnosis includes Linear Atrophoderma of Moulin (LAM) and morphea, where distinctions need to be made to provide a diagnosis to the patient ( Table 2). LAM has typically been reported to have an earlier onset and a distribution following Blaschko's lines.…”

Section: Discussionmentioning

confidence: 99%

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Idiopathic Atrophoderma of Pasini and Pierini: Case report and literature review

Muntyanu

Redpath

Roshdy

et al. 2018

Clinical Case Reports

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Section: Discussionmentioning

confidence: 99%

“…Topical calcineurin inhibitors were found to have variable responses . Q‐switched alexandrite laser has also resulted in some clinical improvement of hyperpigmented lesions …”

Section: Discussionmentioning

confidence: 99%

Idiopathic Atrophoderma of Pasini and Pierini: Case report and literature review

Muntyanu

Redpath

Roshdy

et al. 2018

Clinical Case Reports

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“…The lesion usually progresses very slowly and remains stable for 1–2 decades . Hydroxychloroquine and Q‐switched alexandrite laser have been reported as treatment options for this benign condition . For our patient, a decision was made to observe the lesion.…”

Section: Discussionmentioning

confidence: 99%

An unusual infantile rash

2018

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A 10-month-old white boy presented with a 5-month history of an asymptomatic rash on his lower back. The lesion was not present at birth and the neonatal check was unremarkable. The patient was born at full term via normal vaginal delivery after an uncomplicated pregnancy. He had since met all his developmental milestones and was otherwise well. His medical history included transient infantile seborrhoeic dermatitis of the scalp and temporary failure to thrive secondary to gastro-oesophageal reflux disease, effectively managed with omeprazole. Mild eczema was present in the family history.Physical examination revealed a mildly depressed atrophic patch, 120 9 50 mm in size, with a well demarcated cliff-drop border, on the patient's lower back (Fig. 1a). The lesion crossed the mid-line, and subcutaneous blood vessels were distinctly visible. There was no induration, scarring or lilac ring border. Spinal ultrasonography scan was normal. Histopathological findingsA 6-mm punch biopsy was taken from the lesion border, including areas of normal and atrophic skin for comparison. Figures 2-5 show the histology of the normal skin on the left, while on the right is the corresponding atrophic lesion showing dermal and epidermal atrophy with increased fibroblasts. No inflammation or features of scleroderma were present. Elastic stain showed reduction of elastin (Fig. 5). Staining with Hale colloidal iron for mucin was unremarkable, and S100 staining was negative. Periodic-acid-Schiff did not reveal increased glycogen or any organisms.What is your diagnosis? Figure 1 (a) Well-demarcated atrophic lesion on lower back crossing the mid-line at 10 months of age; (b) at 20 months of age, the size and border of the lesion had remained stable in proportion to the patient's body.

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“…Borelia burgdorferi antikor titresi pozitif olan hastalarda erken dönemde Lyme hastalığı gibi tedavi edilmesi önerilmektedir (13). Q anahtarlı alexandrite lazer ile bir olguda başarılı sonuç elde edilmiştir (14). Hastamızda tedavinin 1. ayında henüz belirgin bir değişiklik saptanamamış olup tedaviye devam edilmektedir.…”

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Pasini ve Pierini'nin idiyopatik atrofoderması

KOÇAK¹

2015

Ankara Üniversitesi Tıp Fakültesi Mecmuası

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Pasini ve Pierini'nin idiyopatik atrofoderması, tek veya çok sayıda keskin sınırlı, hiperpigmente, indurasyon göstermeyen yamalarla karakterli bir dermal atrofi hastalığıdır. Lezyonlar tek veya çok sayıda, yuvarlak veya oval düzensiz șekillidir. Kahverengi, mavimsi, violase renkli olabilir ancak deri yüzeyi normal görünümdedir, endurasyon gözlenmez. Son zamanlarda benzer klinik ve histolojik özellikler nedeniyle lokalize morfeanın yüzeyel bir șekli olduğu ileri sürülmektedir. Burada 17 yașında erkek hastada 3 yıldır olan Pasini Pierini'nin idiyopatik atrofoderması nadir görülmesi nedeniyle sunulmaktadır.

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Treatment of atrophoderma of Pasini and Pierini‐associated hyperpigmentation with the Q‐switched alexandrite laser: A clinical, histologic, and ultrastructural appraisal

Cited by 4 publications

References 12 publications

Idiopathic Atrophoderma of Pasini and Pierini: Case report and literature review

Idiopathic Atrophoderma of Pasini and Pierini: Case report and literature review

An unusual infantile rash

Pasini ve Pierini'nin idiyopatik atrofoderması

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