Treatment of benzodiazepine withdrawal syndrome in a severe traumatic brain injury patient

Abstract

Prolonged exposure to benzodiazepines (BDZ) may contribute towards physical dependence, which is manifested by iatrogenic Benzodiazepine Withdrawal Syndrome (BWS), a condition often underdiagnosed. Current evidence recommends precluding BDZ infusion as sedation in the intensive care unit to avoid possible withdrawal and delirium issues. Administration of dexmedetomidine should be considered to facilitate weaning in patients with BWS.

Acupuncture for ventilator-dependent patients at a hospital-based respiratory care center: A randomized controlled trial

“… 25 , 26 Patients with severe trauma severe traumatic brain injury or with poor Glasgow Coma Scale (GCS) score might have higher risk of exhibiting weaning difficulty. 27 In order to focus on those patients with better prognosis and evaluate the effect of acupuncture therapy, we excluded those cases whose ISS score was higher than 16 or was ST-segment elevation myocardial infarction when admitted to hospital, out-of-hospital cardiac arrest, septic shock, or failure of weaning many times after doing the literature review and discussing with the doctors and nurses in respiratory care center.…”

Ketoacidosis can Be alcohol in origin: A case report

“…The serum ethanol level may be normal or reduced in AKA while it is absent in DKA [ 11 ]. The mainstay of AKA treatment is judicious isotonic fluid therapy to improve cellular hydration, increase renal perfusion, reduce hyperlactatemia and hasten elimination of ketones from the body [ 12 ]. Glucose containing solutions are essential to stimulate release of serum insulin and thus break the cycle of ketogenesis.…”

“…In addition, good sedation in patients at risk of seizure following alcohol withdrawal and allow precise Glasgow Coma Scale (GCS) assessment. In our patient, we chose dexmedetomidine as it possesses excellent anxiolytic and sedative properties [ 12 , 13 ]. Chronic alcohol consumption leads to thiamine deficiency by way of decreased absorption of thiamine from the gastrointestinal tract (GIT) and impaired cellular utilisation [ 14 ].…”

Effect Evaluation of Dexmedetomidine Intravenous Anesthesia on Postoperative Agitation in Patients with Craniocerebral Injury by Magnetic Resonance Imaging Based on Sparse Reconstruction Algorithm

“…Agitation occurs for several reasons, such as surgically related factors, anesthetic factors, and adverse stimuli. At present, the mechanism of postoperative agitation cannot be precisely explained [ 16 , 17 ]. Some scholars believe that the occurrence of postoperative agitation is related to the different degrees of inhibition of the central nervous system by anesthetic drugs [ 11 , 18 ].…”