Treatment of Campylobacter-Associated Enteritis With Erythromycin

Robins‐Browne, Roy M.; Mackenjee, M. K. R.; Bodasing, Marilyn N.; Coovadia, Hoosen M.

doi:10.1001/archpedi.1983.02140290068018

Cited by 19 publications

(17 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Multiple antibiotic resistances refer to resistance to two or more classes of antibiotics. The multiple antibiotic resistances of Salmonella, Shigella, Campylobacter, Aeromonas and Plesiomonas demonstrated in this study accords with other findings (Robins-Browne et al, 1983;Coker and Adefeso, 1994;Asefa et al, 1997;Obi et al, 1997Obi et al, , 1998. Erythromycin used to be the drug of choice for campylobacteriosis but increasing resistance of Campylobacter to erythromycin is well known (Coker and Adefeso, 1994).…”

Section: Antibiotic Susceptibilitysupporting

confidence: 92%

Profiles of antibiotic susceptibilities of bacterial isolates and physico-chemical quality of water supply in rural Venda communities, South Africa

Lawrence¹,

Momba²,

Potgieter³

et al. 2004

WSA

View full text Add to dashboard Cite

The Venda region of South Africa is predominantly rural and residents rely on untreated water sources for daily water needs. The physico-chemical quality of these water sources including antibiotic susceptibilities of enteric bacterial isolates which would guide clinicians in the empiric management of diarrhoea have received cursory attention. This study therefore sought to document the physico-chemical parameters and antibiograms of bacterial isolates from water sources in order to determine the safety for human consumption and to provide updated antibiotic data for empiric treatment of patients. Water samples were obtained on a weekly basis from Ngwedi, Mutale, Tshinane, Mutshindudi and Mudaswali Rivers and Makonde, Mudaswali and Thamathama Fountains between August 2000 and July 2002. Physico-chemical parameters such as turbidity, temperature, pH, lead, fluoride, cyanide, iron, sulphate, chromate and nitrate were determined. Antibiograms of bacterial isolates were ascertained using the disk diffusion method.Results obtained revealed that all the physico-chemical variables of the water sources analysed were within normal recommended limits for safety of drinking water except for turbidity, which exceeded recommended limits and hence precludes the rivers from direct domestic use.Antibiogram profiles showed multiple antibiotic resistances of Salmonella, Shigella, Campylobacter, Aeromonas, Vibrio cholera, Enterobacter and Plesiomonas to ampicillin, tetracycline, chloramphenicol, cotrimoxazole and erythromycin. In contrast virtually all the enteric bacterial isolates showed marked susceptibilities to ciprofloxacin, nalidixic acid, gentamicin, ceftriazone and amikacin. These effective antibiotics are therefore indicated in the empiric treatment of diarrhoeal cases or water-borne diseases of bacterial aetiology.

show abstract

Section: Antibiotic Susceptibilitysupporting

confidence: 92%

Profiles of antibiotic susceptibilities of bacterial isolates and physico-chemical quality of water supply in rural Venda communities, South Africa

Lawrence¹,

Momba²,

Potgieter³

et al. 2004

WSA

View full text Add to dashboard Cite

show abstract

“…Other treatment studies have not demonstrated a decrease in symptoms, in part because the symptoms were too short-lived to measure a significant difference between treatment and control groups (1,12,13,15,16,20). In our study in the orphanage, however, 37% of the treatment group and 35% of the control group still had diarrhea 7 days after therapy was begun.…”

Section: Discussioncontrasting

confidence: 69%

“…In a number of clinical trials performed in adults and children, erythromycin has not been shown to significantly alter the clinical course of Campylobacter infection (1,12,13,15,16,20). Results of one study, however, found that when Peruvian children with bloody diarrhea due to Campylobacter isolates were treated early in the course of illness with erythromycin, they improved earlier than children given placebo (21).…”

mentioning

confidence: 99%

Erythromycin-resistant Campylobacter infections in Thailand

Taylor¹,

Echeverria²,

Pitarangsi³

et al. 1987

Antimicrob Agents Chemother

View full text Add to dashboard Cite

“…Although C jejuni gastroenteritis is often a mild and self limiting illness, one randomised controlled trial indicated that if erythromycin was started at first presentation, before stool culture results were available, the clinical course of the illness was shortened 66. Several other randomised trials in which erythromycin was started after isolation of the organism showed a shortened period of bacterial excretion, but no effect on the clinical course of the illness 67…”

Section: Pharmacotherapymentioning

confidence: 99%

Guidelines for managing acute gastroenteritis based on a systematic review of published research

Murphy¹

1998

Archives of Disease in Childhood

View full text Add to dashboard Cite

This paper is intended to provide evidencebased recommendations about the assessment and clinical management of infants and children with acute gastroenteritis. These guidelines were derived from a systematic review of published research. The diagnosis of gastroenteritis is not addressed; this is often presumptive and is based on a history of acute diarrhoea in the absence of other likely explanations. Microbiological investigation is not necessary in every case, but may be important in patients who require admission to hospital, in those who have bloody or mucoid diarrhoea suggesting colitis, in high risk patients such as those with an immune deficiency, and in cases where there is diagnostic uncertainty. Clinicians should apply general medical knowledge and clinical judgment in using these guidelines. Scope of guidelinesThe topics addressed are: assessment of the risk of dehydration; assessment of the degree of dehydration; oral rehydration therapy (ORT); strategies for rehydration and maintenance of hydration; management of hypernatraemic dehydration; nutritional management during and after the illness; and the role of pharmacological agents including antidiarrhoeals and antimicrobials. Systematic review: search strategy and evaluation of the evidenceThe search was performed using the MEDLINE and Cinahl databases, and covered the years 1966-97. Some relevant articles were also identified from the references cited in publications identified from these databases. The search was limited to studies of human subjects published in English. Subject headings employed were: "gastroenteritis", "diarrhoea", "rehydration solutions", "dehydration", and "hypernatraemia". Textword searches were also done using the terms "infectious diarrh$", "oral rehydration solution$", and "hypernatr$ dehydration". For each topic the terms "review", "metaanalysis", "randomised controlled trial", "cohort study", and "case control study" were applied. The Cochrane Library database of systematic reviews was searched under subject headings. Evidence from the medical literature and the strength of the recommendations given were then categorised according to a previously described scheme (table 1).

show abstract

Treatment of Campylobacter-Associated Enteritis With Erythromycin

Cited by 19 publications

References 16 publications

Profiles of antibiotic susceptibilities of bacterial isolates and physico-chemical quality of water supply in rural Venda communities, South Africa

Profiles of antibiotic susceptibilities of bacterial isolates and physico-chemical quality of water supply in rural Venda communities, South Africa

Erythromycin-resistant Campylobacter infections in Thailand

Guidelines for managing acute gastroenteritis based on a systematic review of published research

Contact Info

Product

Resources

About