The application of the Transcranial Doppler sonography in patients with cervicocranialgia is discussed. The review of the original observation of the state of the arterial and vemous cerebral hemodynamics and cerebrovascular reactivity in these patients is presented. The authors performed clinical and Doppler sonography examinations of 148 patients with cervicocranialgia aged 18 to 45 years. According to the Doppler examination, patients mainly presented with cervicocranialgia, increased velocity parameters and functional asymmetries of blood flow in the basilar and vertebral arteries. Patients with cervicocranialgia had excessive blood supply in vertebral veins and direct sinus. Hyperreactivity in vertebral veins and direct sinus during orthostatic load is probably associated with the impaired regulation of cerebral blood flow at neurogenic level.