Treatment of cherubism with locally aggressive behavior presenting in adulthood: Report of four cases and a proposed new grading system

Motamedi, Mohammad Hosein Kalantar

doi:10.1016/s0278-2391(98)90618-8

Cited by 61 publications

(56 citation statements)

References 13 publications

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“…This pattern was not seen in the children of the cohort, 15 and as far as we know, has not been reported by others, except in a case report of a 27 year old female patient. 16 In our experience, this seems to be a rather common finding in adults.…”

Section: Discussionmentioning

confidence: 50%

Cherubism: panoramic and CT features in adults

Redfors

Jensen²,

Storhaug³

et al. 2013

Dentomaxillofacial Radiology

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Objectives: To describe the panoramic radiographic and CT features of cherubism in an unselected series of 15 adults. Methods: In this cross-sectional study, 15 individuals aged 29-84 years with familial nonsyndromal molecularly confirmed cherubism were examined with panoramic radiography and CT. Bone abnormalities were analysed and described. Results: 11 (73%) of the 15 adults had mandibular abnormalities. These abnormalities ranged from subtly detectable to severe, and were less prevalent and expansive but could be rather similar to the characteristic image features in children. Unilocular radiolucencies were more common than multilocular radiolucencies, and a specific feature of these abnormalities was that they were exclusively found in the anterior mandible. Conclusions: The radiographic and CT abnormalities of cherubism in adults were frequent and extremely heterogeneous, with some distinct features.

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Section: Discussionmentioning

confidence: 50%

Cherubism: panoramic and CT features in adults

Redfors

Jensen²,

Storhaug³

et al. 2013

Dentomaxillofacial Radiology

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“…Cherubism may take various clinical forms, from clinically unapparent with a mild form of cherubism to highly aggressive [10]. premature exfoliation of primary teeth and displacement of the permanent dentition can be observed due to substitution of bone into a fibrous tissue, resulting in occlusophathologie [5]. The treatment plan for cherubic patients must be individually determined for each patient as the severity varies between the cases, RR Addante [11] reported that the extension of lesions, the potential for pathologic fracture, and the high probability of eventual regression must be considered.…”

Section: Discussionmentioning

confidence: 99%

“…Usually The first signs of the disease appear between 1 and 3 years of age [4]. Motamedi [5] proposed a grading system for cherubism in 1998 which was modified by Raposo-Amaral et al [6] in 2007 (Table1). The authors in this article are reporting a case of a 23-year-old male patient with bilateral swelling of the lower jaw which was diagnosed with cherubism grade I class 5.…”

Section: Introductionmentioning

confidence: 99%

Aggressive case of postpubertal cherubism: A case report

Aljumah¹,

Nasser²,

Alomar³

et al. 2017

Dent Oral Craniofac Res

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Cherubism is a non-neoplastic fibro-osseous lesion that is diagnosed among children based on its characterization by bilateral painless enlargement of jaws that offers a cherubic appearance to the affected persons. Cherubism treatment is combative given that it is believed that the lesion regress at puberty but cases with severe facial disfiguration can be corrected surgically. This case reports a 23-year-old male reported to the Department of Oral and Maxillofacial surgery at National Guard Health Affairs, King Abdulaziz Medical City, Riyadh, Saudi Arabia by his mother with chief complaint of asymptomatic, progressive and bilateral enlargement of the mandible. Based on facts and the clinical, historical, family and radio-graphical findings this report prepared a cherubism diagnosis of the patient. The purpose of this case report is to present the unusual postpubertal cherubism.

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“…Bilateral cyst-like lesions are usually limited to the mandible and maxilla, but rare cases of involvement of the zygomatic arches, temporal bone, orbit and condyles have been reported. 25,26 CBCT is very useful tool for the assessment of lesion dimensions, precisely the limits of the lesions, their components, behavior and the exact relation with surrounding structures in cherubism. 27 In our case, CBCT images showed bilateral, large, expansile, multilocular osteolytic lesions with expansion and perforation of the cortical bone at the angle and ramus of the mandible.…”

Section: Discussionmentioning

confidence: 99%