Treatment of childhood obesity: a multidisciplinary approach

Lanigan, Julie; Sauven, Natasha

doi:10.1016/j.intcar.2020.100026

Cited by 4 publications

(2 citation statements)

References 6 publications

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“…In the last two decades, the growing prevalence of childhood obesity observed in many countries has resulted in many efforts from the scientific community to identify the most effective strategies to prevent or treat this condition [ 1 , 2 ]. Among these, multidisciplinary weight-loss interventions, including personalized nutritional and physical activity (PA) plans and psychological support for children and their families, have been recognized as useful measures for childhood obesity treatment [ 2 , 3 ]. With the aim of increasing adherence to PA recommendations, many studies have been focused on motor competence in obese children, showing that this is inversely related to their weight status [ 4 , 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Can a Multidisciplinary Weight Loss Treatment Improve Motor Performance in Children with Obesity? Results from an Observational Study

Gallé

Valerio

Muscariello³

et al. 2023

Healthcare

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In the last two decades, the relationship between weight status and children’s motor skill competence has been receiving increasing attention, given its possible role in the prevention and treatment of obesity. This study aimed to evaluate the effect of a multidisciplinary obesity treatment on motor performance in a sample of Italian children and adolescents. Visual and auditory reaction time (VRT and ART), vertical jump elevation (VJE) and power (VJP), body mass index (BMI) and BMI-standard deviation score (BMI-SDS), waist circumference (WC), body composition, dietary habits and physical activity (PA) levels were assessed at baseline and at 6- and 12-month follow-up. Significant improvements were observed in BMI-SDS and FFM, diet and PA levels. Adolescents showed significant improvements in VRT and ART. Jump elevation and power increased in both children and adolescent subgroups. Girls exhibited greater changes than boys in both VRT and ART and VJP but lower changes in VJE. VRT improvement was related to age (OR = 0.285, 95%CI 0.098–0.830, p = 0.021) and FFM (OR = 0.255, 95%CI 0.070–0.933, p = 0.039). An increase in VJE was associated with BMI-SDS (OR = 0.158, 95%CI 0.036–0.695, p = 0.015) and with PA level (OR = 19.102, 95%CI 4.442–82.142, p < 0.001); the increase in VJP was related with the increase in PA (OR = 5.564, 95%CI 1.812–17.081, p = 0.003). These findings suggest the possible effects of a multidisciplinary obesity treatment on children’s motor competence. Since the improvement in motor skills can increase children’s motivation and adherence to weight loss treatment in the long term, these aspects should be further investigated.

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Section: Introductionmentioning

confidence: 99%

Can a Multidisciplinary Weight Loss Treatment Improve Motor Performance in Children with Obesity? Results from an Observational Study

Gallé

Valerio

Muscariello³

et al. 2023

Healthcare

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“…Beyond the heightened risk of physical health conditions [4][5][6], overweight and obesity also significantly impact the societal and emotional well-being of the youth [7,8]. Clearly, such circumstances hinder the optimal growth and development of children and adolescents, emphasizing the urgency of addressing this matter.…”

Section: Introductionmentioning

confidence: 99%

Pharmacotherapy for Children and adolescents with overweight and obesity: a systematic review and network meta-analysis of randomized controlled trials

Luo,

Huang,

Wang

et al. 2023

Preprint

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Background: Overweight and obesity are widespread among children and adolescents. We aimed to summarize the evidence for the pharmacotherapy as an adjunct to lifestyle interventions in overweight or obese children and adolescents by comparing the benefits and harms. Methods: RCTs (randomized controlled trials) were sourced from PubMed, Embase (using the OVID platform), the Cochrane Library (CENTRAL), as well as the trial registers ICTRP (WHO) and ClinicalTrials.gov. Searches were undertaken from inception to April 25, 2023. A network meta-analysis was performed using the frequentists framework based on random-effects model. We used GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach to evaluate the overall certainty of evidence and categorized the interventions. Results: In total, 42 RCTs (n=3883) comparing 8 different pharmacotherapy strategies were included in this study. Evidence strongly suggested that phentermine-topiramate reduced BMI the most (the mean difference (MD) -4.83 [95% CI, -7.46 to -2.20] kg/m2) and weight (MD, -14.59 [95% CI, -19.37, -9.81] kg) in children and adolescents with overweight or obesity. Compared to lifestyle intervention alone, phentermine-topiramate was associated with an additional 557 events per 1000 person-years in terms of the proportion of participants achieving a BMI reduction of ≥5%, but there was no increased harm in total gastrointestinal adverse effects and discontinuation due to adverse events. Conclusions: Phentermine-topiramate was closely related to weight loss and showed a good tolerability, proving to be the optimal treatment strategy for overweight or obese children and adolescents.

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