Treatment of chondral defects of the knee with one step matrix-assisted technique enhanced by autologous concentrated bone marrow: In vitro characterisation of mesenchymal stem cells from iliac crest and subchondral bone

The treatment of chondral and osteochondral defects of the knee with autologous matrix-induced chondrogenesis (AMIC): method description and recent developments

“…A study of de Girolamo et al [15] suggests a difference in mesenchymal stem cells (MSCs) harvested after microfracturing and primarily from the iliac crest. It is suggested that the MSCs from the microfractured areas demonstrate a different and comparatively irregular pattern than those harvested from the iliac crest.…”

Autologeous matrix induced chondrogenesis (AMIC) for treating articular cartilage defects of the lower limb: A clinical overview

“…Emerging techniques, e.g. the addition of concentrated bone marrow from the iliac crest or platelet rich plasma gel will continue to possibly enhance the AMIC technique 31 .…”

Recent Advances in Egypt for Treatment of Talar Osteochondral Lesions

“…By combining AMIC and BMAC, the cellular component is significantly increased, yielding an even more robust mesenchymal cell niche that can meet the cellular challenge of repairing a critical-sized OCL. 48 Similarly, the AMIC-plus technique has also been described in which the AMIC collagen membrane is saturated with platelet-rich plasma (PRP) in an attempt to increase growth factor content of the scaffold. 49 Due to its most recent evolution, results of AMIC in talar OCLs are limited to a handful of technical surgical notes 50,51 and small case series.…”