Treatment of Chronic Bullous Disease of Childhood

Mintz, Emily M.; Morel, Kimberly D.

doi:10.1007/978-3-662-45698-9_57

Cited by 6 publications

(9 citation statements)

References 14 publications

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“…Treatment-related complications included methemoglobinaemia and, likely, pneumonia and sepsis (7,8,10,14). The relatively short disease course, in most cases ranging from a few weeks to approximately one year (Table SI 1 ), supports a rapid tapering of systemic therapy needed for aerodigestive manifestations.…”

Section: Discussionmentioning

confidence: 97%

A Case of Neonatal Linear IgA Bullous Dermatosis with Severe Eye Involvement

Romani

Diociaiuti²,

D’Argenio³

et al. 2015

Acta Derm Venerol

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Section: Discussionmentioning

confidence: 97%

A Case of Neonatal Linear IgA Bullous Dermatosis with Severe Eye Involvement

Romani

Diociaiuti²,

D’Argenio³

et al. 2015

Acta Derm Venerol

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“…First‐line treatment is dapsone or other sulphonamide antibiotics. Second‐line agents include colchicine and steroids .…”

Section: Aseptic Pustulesmentioning

confidence: 99%

A Review and Proposed Approach to the Neutrophilic Dermatoses of Childhood

Webb

Hlela

Jordaan

et al. 2015

Pediatric Dermatology

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Neutrophilic dermatoses (NDs) are inflammatory skin conditions that are not associated with infection. The classification and clinical approach to these conditions in children is poorly described. This review classifies these conditions into five nosological subtypes: Sweet's syndrome, pyoderma gangrenosum, aseptic pustules, neutrophilic urticarial dermatoses, and Marshall's syndrome. In addition, we review the various secondary diseases that need to be excluded in the clinical management of the NDs of childhood, with a focus on the autoinflammatory conditions that the reader may not be familiar with. We propose a practical clinical approach to these disorders.

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“…Prognosis of AIBD in minors is usually better compared to adults. However, in minors, these diseases usually also require longer immunosuppression with potent topical and oral corticosteroids as well as immunosuppressants and – modulants 7,8 . Clinical trials in children with AIBD are lacking.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and age distribution of pemphigus and pemphigoid diseases among paediatric patients in Germany

Hübner

König

Holtsche

et al. 2020

Acad Dermatol Venereol

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Background Autoimmune bullous diseases are rare and mostly occur in adults. Several cases and small case series have been described in children, but no systematic study about the prevalence of autoimmune bullous diseases (AIBD) in children is available. Patients and methods We analysed data of 1.7 million children insured in the largest German health insurance company based on the ICD-10-GM classification for the year 2015. Data were adjusted to the general German population based on the data of the Federal Statistical Office for the year 2015. Results The prevalence of AIBD was calculated to 101.1/million children in 2015, resulting in about 1351 patients below the age of 18 years in Germany. The highest prevalence of all AIBD was seen for pemphigus vulgaris (30.5/million children) followed by linear IgA disease (24.5/million children) and bullous pemphigoid (4.9/million children). Conclusion Autoimmune bullous diseases in minors are scarce but should be taken into consideration in patients with pruritus and/or blisters and erosions on the skin and/or mucous membranes. Treatment is challenging, and due to the rarity of AIBD in minors, the management of these disorders in this patient population is best performed in specialized centres in a multidisciplinary approach, including paediatric dermatologists or dermatologists and paediatricians.

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Treatment of Chronic Bullous Disease of Childhood

Cited by 6 publications

References 14 publications

A Case of Neonatal Linear IgA Bullous Dermatosis with Severe Eye Involvement

A Case of Neonatal Linear IgA Bullous Dermatosis with Severe Eye Involvement

A Review and Proposed Approach to the Neutrophilic Dermatoses of Childhood

Prevalence and age distribution of pemphigus and pemphigoid diseases among paediatric patients in Germany

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