Treatment of Chronic Colpo-Vaginitis by Stimulation of the Immune System

Abstract

We evaluated 100 patients with chronic colpo-vaginitis treated with the immunotherapeutic Gynatren/SolcoTrichovac. 44 patients suffered from ‘non-specific’ vaginitis, 42 were infected with Candida albicans and 14 with Chlamydia vaginalis. All patients had had several episodes of vaginal infections, some of them over several years, and 53 patients had current infection which, despite treatment with various drugs and remedies, had already persisted more than 2 months. The treatment consisted of 3 intramuscular injections at intervals of 2 weeks. Four weeks after beginning treatment all patients were free from pain despite the fact that the immune response was not yet fully developed. Four weeks later 72 % were classified as cured or much improved and 6 months after beginning therapy 49 of the 89 patients examined at this time were cured and a further 11 patients presented with only ‘mild symptoms’.

Bacterial Vaginitis: Protection against Infection and Secretory Immunoglobulin Levels in the Vagina after Immunization Therapy with Gynatren®

“…Moreover, in the placebo group a total of 125 separate reinfec tions had to be treated, while in the immu nized group only 67 new infections ap peared. These figures, as far as they can in fact be compared with the earlier studies of Harris [9], Litschgi [14] and Verling [24] and in view of the differences in methodology, confirm the positive experience with this immunization therapy made earlier by these authors and by ourselves [4], It has to be borne in mind that the partners of the treated women were not investigated as to whether they had any transmissible infec tion, such as G. vaginalis, or not. Furthermore, as we had no information on sexual promis cuity, only speculation could be made on the risk of these women becoming re-infected by sexual contact.…”