Treatment of Chronic Osetomyelitis by Saucerization and Gentamicin - PMMA Beads

An Interventional Study on Antibiotic Cement-coated Nails and Cement Beads in the Management of Infected Nonunion of Long Bones

“…Complete debridement, firm fixation, and the use of high-dose antibiotics are the recommended treatment for infected nonunion of the long bone. 1,6,13,14 Several procedures have been tried for the better management of the same and intramedullary devices were used in both primary and secondary stages of infection control 8,9 and bone healing, 15 respectively, with remarkable outcomes. 16 Sinus tract culture reports were negative in some of the studies, where they reported it to have poor diagnostic efficacy.…”

“…In the past decades, the incidence of infected nonunion shows a steady increase due to a high rate of trauma from road traffic accidents, industrial injuries leading to open fractures, postoperative infection following open reduction and internal fixation (ORIF), and injurious use of antibiotics resulting in resistant strains of bacteria when compared with past when chronic osteomyelitis was the major cause of infected nonunion. 1 Causes of infected nonunion are usually inherent to the fracture, like an open wound, loss of soft tissue or bone, severe comminution and gross displacement, vascular compromise, deep-seated infection at fracture area, periosteal stripping, etc. 2 In infected nonunion, secondary infections are common and multiple organisms may grow from cultures taken from sinus tracts and open biopsy specimens of surrounding soft tissue and bone.…”