1990
DOI: 10.1182/blood.v76.3.435.bloodjournal763435
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Treatment of Cooley's anemia [see comments]

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Cited by 28 publications
(37 citation statements)
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“…Rebellion against starting such therapy during adolescence is well recognised. 16 In contrast most who began desferrioxamine in eary childhood were compliant. These patients benefitted from initial parental supervision and in a sense they 'grew up with desferrioxamine'.…”
Section: Discussionmentioning
confidence: 99%
“…Rebellion against starting such therapy during adolescence is well recognised. 16 In contrast most who began desferrioxamine in eary childhood were compliant. These patients benefitted from initial parental supervision and in a sense they 'grew up with desferrioxamine'.…”
Section: Discussionmentioning
confidence: 99%
“…Individuals who inherit two P-thalassemia alleles usually present early in childhood with severe anemia requiring lifelong transfusion and iron chelation therapy, a phenotype described as p-thalassemia major. Despite significant advances in the management of p-thalassemia major (Fosburg and Nathan, 1990), affected individuals have reduced life expectance due to the long-term effects of iron overload in major organs (Zurlo et al, 1989).…”
Section: Introductionmentioning
confidence: 99%
“…They were all receiving desferroxiamine as chelation therapy (25-50 mg/kg body wt s.c. infused 4-6 days a week to maintain serum ferritin level below 1,300 ng/ml) for prevention of iron toxicity. 19 Hematological data are summarized in Table I.…”
Section: Patient Populationmentioning
confidence: 99%