Treatment of experimental hemorrhage with colloid-crystalloid mixtures

Gollub, S; Kangwalklai, Kiat; Schaefer, Clara

doi:10.1016/0022-4804(69)90072-9

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Intravascular Volume Expansion1

Survival Rate1

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1969

2012

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Cited by 7 publications

(2 citation statements)

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“…Most studies have examined high molecular weight hetastarch or dextran 70, with estimates of the immediate post‐infusion plasma volume expansion varying from 70 to 170% of infused volume. This later falls to approximately 50% of infused volume after 6 hours (Gollub et al. 1969; Hempel et al.…”

Section: Intravascular Volume Expansionmentioning

confidence: 99%

Fluid therapy with artificial colloids: complications and controversies

Hughes

2001

Veterinary Anaesthesia and Analgesia

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Section: Intravascular Volume Expansionmentioning

confidence: 99%

Fluid therapy with artificial colloids: complications and controversies

Hughes

2001

Veterinary Anaesthesia and Analgesia

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“…This loss, increasing the blood viscosity, slows the blood flow even more, especially at the level of the venous system, with as a consequence, the re trograde increase of the hydrostatic pressure. At this stage, the adminis tration of sympathicomimetics is contraindicated since it only aggravates the situation, increasing the resistance in the postcapillary venous system with retrograde increase of the hydrostatic pressure [1,10,17,20],…”

Section: Survival Ratementioning

confidence: 99%

Interest of Isoproterenol in the Treatment of Hemorrhagic Shock in Dogs

Rettmann¹,

C²

1976

Eur Surg Res

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Four groups of experiments were focused on two problems: first, the replacement of the substracted amount of blood, and second, the correction of the peripheral reactions to substantial blood loss, namely vasoconstriction and acidosis. We stuck to a simple plan in our experiments: lost blood was entirely collected and retransfused. In 26 cases out of 37, we used isoproterenol hydrochloride (Isuprel®-WINTHROP) to open the peripheral vascular bed. In six different groups, we followed the response to variations of retransfusion and administration of isoproterenol. Several parameters were studied: arterial blood pressure, central venous pressure, rectal temperature and pH. The association of blood transfusion with injection of isoproterenol, in adequate amounts to correct hypovolemia and to prevent vasoconstriction, is undoubtedly the best treatment of hemorrhagic shock.

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