Treatment of fetal anemia in Rh isoimmunized pregnancies with intrauterine fetal blood transfusion

Vatsla, Dadhwal; Deka, Deepika; Gurunath, Sumana; Mittal, Suneeta; Paul, Vinod K.; Deorari, Ashok K.

doi:10.1007/s13224-010-0019-y

Cited by 7 publications

(7 citation statements)

References 12 publications

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“…Due to favorable cervix in multiparous women, vaginal delivery with intrapartum electronic monitoring was successful in 25% cases. Vatsala et al [12] in their study reported an incidence of vaginal delivery by 32.5%.…”

Section: Discussionmentioning

confidence: 86%

“…Forty-five percentage of the fetuses were delivered at near-term gestation (34-36 weeks), thus minimizing the morbidity and mortality due to prematurity. Vatsala et al [12] reported 30% of the fetuses were delivered at near-term gestation.…”

Section: Discussionmentioning

confidence: 99%

“…Management of moderate to severe fetal anemia with ultrasonography and by intrauterine blood transfusions has dramatically improved the survival rate of babies in Rhisoimmunized mothers. It is, however, a difficult procedure associated with fetal mortality (4.8%) [11,12].…”

Section: Discussionmentioning

confidence: 99%

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Perinatal Outcome After Intrauterine Transfusion in Rh Isoimmunized Mothers

Potdar

Narkhede

Satoskar

2018

J Obstet Gynecol India

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Objective The objective of the study was to assess the fetal outcome after receiving intrauterine transfusion (IUT) in Rh-isoimmunized pregnancy in a tertiary care center. Study Design This was a retrospective observational descriptive study in which all Rh-negative gravidas with isoimmunization warranting IUTs (40 patients) were analyzed during the period from January 1, 2010 to October 31, 2015. Primary outcome variables were fetal outcomes and procedural-related factors. Results Forty pregnancies (13-hydropic, 27-non-hydropic) required 74 IUTs. IUT was performed at gestational age of 15.4-33 weeks when indicated. The amount of blood transfused ranged from 4 to 110 ml. There were two sudden intrauterine fetal deaths during the procedure,

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Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

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Perinatal Outcome After Intrauterine Transfusion in Rh Isoimmunized Mothers

Potdar

Narkhede

Satoskar

2018

J Obstet Gynecol India

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“…Intrauterine blood transfusion to the fetus was found to be the only lifesaving therapy, and very useful. The early referral to specialized centers with the expertise of specialized intensive fetal monitoring for early diagnosis of fetal anemia and intrauterine fetal blood transfusion is essential for optimal perinatal outcomes [3].…”

Section: Discussionmentioning

confidence: 99%

“…During the first two decades of the new millennium, in-utero management of these anomalies became feasible due to the evolution of fetoscopy and the extended role of fetoscopic surgeries. Also, the progress of fetoscopic surgeries became prominent in the treatment of some fetal anomalies like lower urinary tract obstruction (LUTO), hydrothorax, and fetal anemia [3]- [11].…”

Section: Introductionmentioning

confidence: 99%

Fetoscopy Role in Fetal Surgery and Fetal Medicine

Elbanna¹,

Oun²,

Ellatif³

et al. 2019

OJOG

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Aim: We attempted to illustrate our experience of fetoscopic therapy in a tertial institute, whereby to highlight the present Egyptian situation regarding this issue. We described fetoscopic therapy undergone at Al-Hussein Hospital, Al-Azhar University, Cairo, Egypt, from Dec-2012 to Sep-2019. Presentation of cases: Sixteen women with 17 fetuses were included in the analysis of this study with a mean age of 25.31 ± 6.15 years; four with positive marriage to a near relevant, and eight were primigravida. The fetus of twelve women had lower urinary tract obstruction (LUTO), two fetal anemia, one hydrothorax, and one twin-to-twin transfusion syndrome (TTTS). The mean time for fetoscopy was gestational week 24.13 ± 3.77. We did therapeutic drainage to amniotic fluid in hydrothorax and LUTO, therapeutic septostomy to the TTTS case, and blood transfusion in cases of fetal anemia. During the operation, the procedure succeeded in 14 out of 16 women. Overall, nine of the 16 women experienced some complications; five with rupture of membranes, four with preterm labor, and three with intrauterine fetal death (IUFD). Conclusion: Fetoscopy can manage LUTO and well-selected cases of TTTS, hydrothorax, and fetal anemia. The procedure is promising. Fetoscopic therapy has just begun in Egypt, and this report may contribute to the future advance of fetoscopic therapy in Egypt.

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