Treatment of flat warts with 5% imiquimod cream

Mb, Kim; Hc, Ko; Hs, Jang; Ck, Oh; Ks, Kwon

doi:10.1111/j.1468-3083.2006.01709.x

Cited by 10 publications

(4 citation statements)

References 4 publications

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“…130 There are numerous case reports reporting the effectiveness of imiquimod in both immunocompetent and immunocompromised patients. 131,132 It has a tolerable sideeffect profile with mild-to-moderate local pain reported most frequently.…”

mentioning

confidence: 99%

British Association of Dermatologists' guidelines for the management of cutaneous warts 2014

et al. 2014

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confidence: 99%

British Association of Dermatologists' guidelines for the management of cutaneous warts 2014

et al. 2014

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“…Excellent results in a group of patients suffering mild/moderate wart were higher than that of the group having severe wart (82.8% vs 45.5%, p = 0.03). So longer the duration of disease was, the less effective the treatment modality was [4], [5], [6].…”

Section: Discussionmentioning

confidence: 99%

Early Treatment with Imiquimod 5% Cream of Periungual Warts in Vietnam: The Poorer, the Better

Minh¹,

Thi²,

Lan³

et al. 2019

Open Access Maced J Med Sci

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AIM: To evaluate the efficacy of imiquimod 5% in periungual wart treatment. MATERIAL AND METHODS: A group of 40 patients were recruited to apply imiquimod 5 % cream once daily for 5 consecutive days per week in 8 weeks. They were classified into 3 levels: Mild (the total lesion area ≤ 25 mm2), moderate (25 mm2 <total lesion area ≤ 50 mm2), severe (total lesion area > 50 mm2). The outcome was evaluated at the 4th and the 8th week. The result was graded as excellent (complete clearance), good (≥ 50% clearance) and poor (< 50% clearance). RESULTS: The total area of the wart lesion got decreased significantly from the beginning to the 4th and the 8th week (36.7 mm2 vs 16.8 mm2, p = 0.0001 and 16.8 mm2 vs 8.8 mm2, p = 0.01). The complete clearance rate at the 4th week was lower than that at the 8th week significantly (22.5% vs 72.5%, p = 0.04). The clearance rate of patients suffering severe warts was lower significantly than that of mild/ moderate patients (82.8% vs 45.5%, p = 0.03). The duration of the disease in people who responded completely to imiquimod was shorter than that of patients partially responded (10.2 ± 14.1 months vs 22.3 ± 14.3 months, p = 0.02). Adverse effects were not common, mild and local only. Recurrence rate after 6 months of follow up was 3.5%. CONCLUSION: In conclusion, Imiquimod 5% cream is a safe and effective drug in the treatment of periungual warts.

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“…For flat warts, however, and warts in areas where the other treatments may be undesirable or untenable, imiquimod can be helpful. 39 As there is no set dosing regimen for such off-label uses, one can have the patient titrate the applications until a mild but tolerable inflammatory response develops. Starting at three times weekly, the frequency can be increased to up to twice daily or down to once weekly or every other week.…”

Section: Wartsmentioning

confidence: 99%

Warts, molluscum and things that go bump on the skin: a practical guide

Lio¹

2007

Archives of Disease in Childhood - Education and Practice

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Treatment of flat warts with 5% imiquimod cream

Cited by 10 publications

References 4 publications

British Association of Dermatologists' guidelines for the management of cutaneous warts 2014

British Association of Dermatologists' guidelines for the management of cutaneous warts 2014

Early Treatment with Imiquimod 5% Cream of Periungual Warts in Vietnam: The Poorer, the Better

Warts, molluscum and things that go bump on the skin: a practical guide

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