Treatment of Fungal Urinary Tract Infection

Management of fungus balls as a result of Candida albicans

“…Diabetes mellitus, indwelling catheter use, recent antimicrobial use, immunosuppression, neurogenic bladder and urolithiasis have been reported to be strong risk factors for funguria. 3 In the present case, he had chronic systemic steroid therapy, recent use of antibacterial agents and benign prostatic hyperplasia.According to the review article by Fisher et al, the algorithm shows that the treatment for fungus balls is oral administration of fluconazole 400 mg daily for 4 weeks, flucytosine four times a day for 2-4 weeks or intravenous injection of amphotericin B (the duration has not been established). 4 Additionally, the patient should have the indwelling urethral catheter removed as soon as possible, because this results in clearance of the funguria.…”

“…Diabetes mellitus, indwelling catheter use, recent antimicrobial use, immunosuppression, neurogenic bladder and urolithiasis have been reported to be strong risk factors for funguria. 3 In the present case, he had chronic systemic steroid therapy, recent use of antibacterial agents and benign prostatic hyperplasia.…”

“…5 Invasive procedures, such as irrigation or transurethral resection of fungal balls, might need to be carried out to relieve the obstruction. 3 In the present case, because urinary tract infection caused by fungi was not diagnosed at the first cystoscopy, transurethral resection was not carried out. The attending physician decided the dose and duration of administration of the antifungal agent according to the patient's symptoms.…”

“…Additionally, the patient should have the indwelling urethral catheter removed as soon as possible, because this results in clearance of the funguria . Invasive procedures, such as irrigation or transurethral resection of fungal balls, might need to be carried out to relieve the obstruction . In the present case, because urinary tract infection caused by fungi was not diagnosed at the first cystoscopy, transurethral resection was not carried out.…”

Editorial Comment to Management of fungus balls as a result of Candida albicans

“…reported that strong risk factors for funguria included diabetes mellitus, indwelling catheter use, recent antibiotic use and urinary tract disease. They also reported that the possible risk factors included pregnancy, malignancy, immunosuppression, recent surgery and renal transplant . Sobel et al .…”