Treatment of hidradenitis suppurativa with intralesional photodynamic therapy using a laser diode attached to an optical cable: a promising new approach

Valladares-Narganes, Luis Miguel; Rodríguez-Prieto, Manuel Ángel; Blanco-Suárez, M.D.; Rodriguez-Lage, C.; García‐Doval, I.

doi:10.1111/bjd.13385

Cited by 43 publications

(39 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There appears to be RCT evidence behind using follicular laser ablation for early stage disease . Response to photodynamic therapy is variable; larger and randomized controlled trials are needed. External beam radiation therapy has an unclear role in the treatment of HS, as there are currently only case reports in the literature …”

Section: Scientific Session 6: Surgical and Laser Management Of Hidramentioning

confidence: 99%

Proceeding report of the third symposium on Hidradenitis Suppurativa advances (SHSA) 2018

Rios

Sarfo

Ghias

et al. 2019

Experimental Dermatology

View full text Add to dashboard Cite

The 3rd Annual Symposium on Hidradenitis Suppurativa Advances (SHSA) took place on 12‐14 October 2018 at the Women's College Hospital in Toronto, Ontario, Canada. This symposium was a joint meeting of the Hidradenitis Suppurativa Foundation (HSF) founded in the USA and the Canadian Hidradenitis Suppurativa Foundation (CHSF). This cross‐disciplinary meeting with experts from around the world was an opportunity to discuss the most recent advances in the study of hidradenitis suppurativa pathogenesis, epidemiology, classification, scoring systems, radiologic diagnosis, treatment approaches and psychologic assessment. Two special sessions this year were HS as a systemic disease and HS management guidelines. There were focused workshops on wound healing and ultrasound. There were two sessions primarily for patients and their families in the HS School programme: One workshop focused on mindfulness, and the second involved discussion among clinicians and patients about various disease aspects and the latest management. To facilitate networking between clinical and research experts and those early in their career, a mentoring breakfast was held.

show abstract

Section: Scientific Session 6: Surgical and Laser Management Of Hidramentioning

confidence: 99%

Proceeding report of the third symposium on Hidradenitis Suppurativa advances (SHSA) 2018

Rios

Sarfo

Ghias

et al. 2019

Experimental Dermatology

View full text Add to dashboard Cite

show abstract

“…In these cases, treatments were more tolerable for subjects treated with blue light than with intense pulsed light. Uncertain results have been obtained with intralesional PDT [74][75] . Agut-Busquet et al [76] recently reported a retrospective experience in the treatment of HS with PDT using intralesional methylene blue and a 635-nm light-emitting diode lamp in 7 patients.…”

Section: Hidradenitis Suppurativamentioning

confidence: 99%

Photodynamic Therapy and Skin Appendage Disorders: A Review

Megna

Fabbrocini

Marasca

et al. 2016

Skin Appendage Disord

View full text Add to dashboard Cite

Photodynamic therapy (PDT) is a noninvasive treatment that utilizes light treatment along with application of a photosensitizing agent. In dermatology, PDT is commonly used and approved for the treatment of oncological conditions such as actinic keratosis, Bowen disease and superficial basal cell carcinoma. In the last 2 decades however, PDT has also been used for the treatment of several nonneoplastic dermatological diseases. The present review summarizes published data on PDT application in skin appendage disorders. Our literature review shows that: (a) PDT may be a suitable treatment for acne, folliculitis decalvans, hidradenitis suppurativa, nail diseases, and sebaceous hyperplasia; (b) there is a lack of agreement on PDT features (type, concentrations and incubation period of used substances, number and frequency of PDT sessions, optimal parameters of light sources, and patient characteristics [e.g., failure to previous treatments, disease severity, body surface area involved, etc.] which should guide PDT use in these diseases); (c) further research is needed to establish international guidelines helping dermatologists to choose PDT for the right patient at the right time.

show abstract

“…Recently, RodriguezPrieto et al used intralesional PDT for the treatment of HS and showed good e®ect. 16,17 Intralesional PDT will be a good choice for late sinus/¯stula lesions. Saraceno et al reported a case of HS achieved 80% remission of skin lesions treated by nine times of Methyl aminolaevulinate PDT.…”

Section: Discussionmentioning

confidence: 99%

Topical 5-aminolevulinic acid photodynamic therapy improved refractory acne conglobata and perifolliculitis capitis abscedens et suffodiens rather than hidradenitis suppurativa

Zhang

Wang

Shi

et al. 2016

J. Innov. Opt. Health Sci.

View full text Add to dashboard Cite

Acne conglobata (AC), perifolliculitis capitis abscedens et su®odiens (PCAS) and hidradenitis suppurativa (HS) are uncommon refractory chronic, in°ammatory, scarring diseases but cause serious damage to the quality of life. These three diseases are associated with follicular occlusion. Several studies indicated topical 5-aminolevulinic acid photodynamic therapy (ALA-PDT) improved follicular occlusion besides acne treatment. So we attempted to apply ALA-PDT to medicine resistant AC, PCAS and HS. Topical ALA-PDT was applied to 10 patients with AC, seven patients with PCAS and three patients with HS for more than three sessions. All the patients completed the dermatology life quality index (DLQI) questionnaire and were assessed for the e±cacy at the baseline and on two weeks after each treatment. Adverse e®ects were recorded at each visit. The results showed 25.5% (5/20, two cases of AC and three cases of PCAS) of patients achieved excellent improvement after three sessions of PDT and another 60. HS) got poor response (< 20% lesions clearance). Another¯ve cases (three cases of AC and two cases of PCAS) also achieved excellent response after 5-7 sessions of PDT. We also found that papular/nodular, cyst/abscess showed higher clearance rate than sinus/¯stula (88.5%, 86.1% versus 11.1%). DLQI was reduced after three sessions of PDT in AC and PCAS patients rather than HS patients. 5-ALA-PDT could improve refractory AC and PCAS but could not lead to improvement in late stage of HS. The e±cacy increased with more treatment sessions.

show abstract

Treatment of hidradenitis suppurativa with intralesional photodynamic therapy using a laser diode attached to an optical cable: a promising new approach

Cited by 43 publications

References 10 publications

Proceeding report of the third symposium on Hidradenitis Suppurativa advances (SHSA) 2018

Proceeding report of the third symposium on Hidradenitis Suppurativa advances (SHSA) 2018

Photodynamic Therapy and Skin Appendage Disorders: A Review

Topical 5-aminolevulinic acid photodynamic therapy improved refractory acne conglobata and perifolliculitis capitis abscedens et suffodiens rather than hidradenitis suppurativa

Contact Info

Product

Resources

About