Treatment of Horizontal Neck Wrinkles with Hyaluronic Acid Filler: A Retrospective Case Series

Tseng, Fang-Wen; Yu, Hsiaoen

doi:10.1097/gox.0000000000002366

Cited by 20 publications

(24 citation statements)

References 33 publications

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“…Tseng et al showed that the score based on a horizontal neck fold severity scale improved after 1 month of the first injection, while the improvement peaked at 2 and 4 weeks after a single touch-up following the first dose, one month later. After that period, the improvement slightly diminished but was still significant from baseline till the end of follow-up [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Clinical Efficacy and Safety of Non-Cross-Linked Hyaluronic Acid Combined with L-carnosine for Horizontal Neck Wrinkles Treatment

Wang¹,

Niu²,

Liu

et al. 2021

Aesth Plast Surg

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Background Horizontal neck wrinkle formation is gaining more attention among cosmetic practitioners and clients. To date, hyaluronic acid products are one of the most common treatment options for this aesthetic concern. However, different therapeutic strategies should be given to solve the problem due to multiple etiological reasons. Given that oxidative damage plays a critical role in neck wrinkle formation, anti-oxidative compounds are now considered by physicians when making a treatment plan. Aims To evaluate the efficacy and safety of a non-cross-linked hyaluronic acid filler in combination with L-carnosine in treating horizontal neck wrinkles. Methods Thirteen patients with a Wrinkle Assessment Scale (WAS) of 2–5 for horizontal neck wrinkles were treated with L-carnosine-containing non-cross-linked hyaluronic acid. Participants were followed-up for 3 months after treatment. The post-treated WAS scores evaluated by physicians were collected when patient satisfaction was surveyed. Any post-treatment adverse events were recorded. Results With a single injection of the above filler, the physician-evaluated WAS scores improved by at least one score at one month and the improvement kept consistent as far as three months after injection. According to the last follow-up visit, 11/13 patients were satisfied with the treatment effect of their neck wrinkle. Moreover, adverse events were rare after filler injection, except for local complications that were considered common reactions to the filler injection procedure. Conclusion The non-cross-linked hyaluronic acid filler containing L-carnosine is safe and effective for treating horizontal neck wrinkles.Level of Evidence IV This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

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Section: Discussionmentioning

confidence: 99%

Clinical Efficacy and Safety of Non-Cross-Linked Hyaluronic Acid Combined with L-carnosine for Horizontal Neck Wrinkles Treatment

Wang¹,

Niu²,

Liu

et al. 2021

Aesth Plast Surg

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“…They include injection site-related reactions of mild intensity, including erythema, pruritus, ecchymosis, and localized swelling. [18] Cryolipolysis Cryolipolysis is a popular technique that produces non-invasive fat reduction by controlled cooling of adipocytes that is widely used to treat various locations on the body including submental fat. As with treatment elsewhere in the body, cryolipolysis of submental fat may require multiple sessions to achieve the desired effect.…”

Section: Treatmentmentioning

confidence: 99%

Characteristic features of neck aging

Vedamurthy¹,

Hande²

2022

CSDM

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In today’s era, everyone desires a youthful and beautiful look as they age. In this regard, many non-invasive and minimally invasive facial and neck rejuvenation procedures are most sought after by patients. Neck rejuvenation is of priority among patients in recent days as it significantly contributes to the overall aesthetic outcome. Therefore, as good dermatologists, we must have a sound knowledge of the anatomy of the neck, and various clinical signs of neck aging and choose the right modality of treatment with good acceptability and fewer adverse effects to obtain the desired aesthetic outcome. Neck aging is due to intrinsic as well as extrinsic factors and manifests as skin dyspigmentation, laxity, rhytides, loss of mandibular contour, widening of the cervicomental angle, accumulation of submental fat, volume loss, and prominence of the platysmal bands. A wide range of therapeutic options is available to address these concerns. In addition, it is also imperative to advise patients to follow a good skincare regime that includes moisturizers, sunscreens, and retinol creams to have a better outcome. It is the combination approach that often produces the most optimal outcome. The treatment plan for rejuvenation must be modified for every individual based on the degree of neck aging and their expectations.

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“…Most studies available are retrospective in nature and use the sharp needle technique. This prospective study aims to evaluate the efficacy and safety of an HA filler on the treatment of horizontal neck lines by blunt cannula injection technique 2–5 …”

Section: Introductionmentioning

confidence: 99%

Efficacy and safety of hyaluronic acid filler on the treatment of horizontal neck lines

Rongthong

Wanitphakdeedecha

Maiprasert

et al. 2022

J of Cosmetic Dermatology

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Background: Injection of hyaluronic acid fillers (HA) fillers for horizontal neck line correction and rejuvenation has gained popularity in recent years despite conflicting reports on its efficacy and safety. Most published reports are retrospective studies that commonly use the sharp needle technique. In this prospective study, we therefore aimed to determine the efficacy and safety of an HA filler (Belotero Balance®, Merz Aesthetics) on the treatment of horizontal neck lines by blunt cannula injection technique.Materials and Methods: Thirty subjects were enrolled and treated with HA filler injections on the neck region using a blunt cannula injection technique into the deep dermis. Standardized photographic documentation was done at baseline, immediately after injection, and at 2-week, 1-, 3-, and 6-month follow-up after treatment. The rejuvenation effect was graded by the patients themselves and two blinded dermatologists using comparative photographs. Side effects were likewise recorded at each follow-up visit.Results: All 30 subjects completed treatment and attended every follow-up visit. The study participants comprised both females and males aged 20-69 years with mild, moderate, and severe neck lines based on the Horizontal Neck Wrinkle Severity Scale (HNWS) (Plast Reconstr Surg Glob Open, 2019, 7, 2366. All patients received approximately 3 ml of HA fillers for the entire treatment area. Both patient and physician ratings revealed peak benefits at 1-month post-treatment, with a significant decline at 3 months, which was sustained until 6 months after the procedure. Only one patient developed bruising related to the treatment, which resolved spontaneously without any additional medication. Conclusion:The study demonstrated efficacy in improving the appearance of horizontal neck lines after one session of HA filler injection. The results showed peak

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Treatment of Horizontal Neck Wrinkles with Hyaluronic Acid Filler: A Retrospective Case Series

Abstract: Supplemental Digital Content is available in the text.

Cited by 20 publications

References 33 publications

Clinical Efficacy and Safety of Non-Cross-Linked Hyaluronic Acid Combined with L-carnosine for Horizontal Neck Wrinkles Treatment

Clinical Efficacy and Safety of Non-Cross-Linked Hyaluronic Acid Combined with L-carnosine for Horizontal Neck Wrinkles Treatment

Characteristic features of neck aging

Efficacy and safety of hyaluronic acid filler on the treatment of horizontal neck lines

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