Treatment of Human Skin Burns Through Using Tilapia Skin

Abstract

Burns are medical conditions that are the fifth major reason behind non-fatal and adult injuries due to compulsiveness and a lack of risk calculation ability. 1.2 In Pakistan, 2500 children suffer serious burns that necessitate medical attention each year, with 15,000 requiring hospitalizations. The WHO (World Health Organization) has revealed in the reports that child burn mortality is greater (seven times) in countries with low and middle-income backgrounds compared to those with high incomes. Polypeptides of varied molecular weights were discovered in MCPs. These MCPs come from Nile tilapia’s skin with the help of enzyme-aided hydrolysis, with polypeptides with a molecular weight smaller than 5kDa accounting for 99.1 percent of the total. The key molecular conformations within MCPs were casual coil, according to FTIR. The MCPs application was done in the quantity of 50g/ml. The treatment significantly affected scratch closure in an in vitro scratch assay. MCPs improve wound healing in rabbits with a deep partial-thickness scald wound. As a result, it was concluded that the MCPs derived from Nile tilapia‘s skin have promising wound care effects and results.

Adipose-Derived Stem Cells (Adscs) Pretreated With Vascular Endothelial Growth Factor (Vegf) Promoted Wound Healing in Rat Skin Burn Model

“…ADSCs can be differentiated into adipogenic, chondrogenic, osteogenic and myogenic lineages by important inducing factors. Adipose-derived stem cells secrete different vital growth factors and cytokines, which are very significant and critical for tissue repair and regeneration (Zuk et al, 2001;Riaz, 2021). Burn lesions cause mortality and disability everywhere in the world.…”