Treatment of In-stent Restenosis of the Internal Carotid Artery Using Drug-eluting Balloons

Marton, Annamária; Blényesi, Eszter; Török, Katalin; Balogh, Gábor; Gubucz, István; Nardai, Sándor; Lenzsér, Gábor; Nagy, Csaba; Bajzik, Gábor; Tollár, József; Repa, Imre; Nagy, Ferenc; Vajda, Zsolt

doi:10.1007/s00062-023-01343-6

Clin Neuroradiol

2023

DOI: 10.1007/s00062-023-01343-6

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Treatment of In-stent Restenosis of the Internal Carotid Artery Using Drug-eluting Balloons

Annamária Marton,

Eszter Blényesi,

Katalin Török

et al.

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2024

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Cited by 2 publications

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“…In cardiovascular diseases (CVDs), plaque accumulates in the coronary artery and affects blood flow, − resulting in a lack of oxygen or nutrition in the heart that can lead to death. The American Heart Association annually releases statistical reports on heart disease, stroke, and cardiovascular risk factors, and considerable research efforts are devoted to CVD. , This focus includes artificial polymer bypass graft transplants, ,− stent material innovations, antithrombosis medicine studies, ,− tissue engineering for artificial vascular grafts, ,, tissue repair medicine for ischemia, ,− and creating biomarkers for detection. ,,, …”

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confidence: 99%

Rapid-Test Kit for Cardiac Troponin I: A Reliable Enzyme-Linked-Immuno-Substrate-Assay-Based Biosensor for Daily-Use Naked-Eye Detection and Pharmacokinetic Studies for Myocardial Infarction in Cardiovascular Disease

Hsieh,

Lin

2024

ACS Pharmacol. Transl. Sci.

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Myocardial infarction (MI) is a severe cardiovascular event that can lead to death. Cardiac troponin I (cTnI) is an MI biomarker in the circulation system; however, methods for detecting cTnI protein require substantial time, tedious operations, an expensive reader for translating signals, and a lot of reagents. This study aims to create a cTnI protein test kit with results easily distinguished by color differences, explicitly focusing on the resolution between different concentrations that eyes can discern. These results will aid in creating a commercial, portable, convenient, daily-use rapid-test kit. This study proposes a cTnI biosensor that the naked eye can perceive, performs diagnoses based on pattern color, does not require a reader machine, is easy to operate, and is portable. Our device shortens diagnosis time, has a 0.32−200 ng/mL quantitative analysis range in the human serum matrix, achieves a 0.32 ng/mL limit of detection, and exhibits many advantages compared to a traditional cTnI ELISA plate.

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mentioning

confidence: 99%

Rapid-Test Kit for Cardiac Troponin I: A Reliable Enzyme-Linked-Immuno-Substrate-Assay-Based Biosensor for Daily-Use Naked-Eye Detection and Pharmacokinetic Studies for Myocardial Infarction in Cardiovascular Disease

Hsieh,

Lin

2024

ACS Pharmacol. Transl. Sci.

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Drug-Coated Balloon Angioplasty for In-Stent Restenosis in the Vertebral Artery Ostium: Experiences From a Single Center

Xu,

Shen,

Wang

et al. 2024

Vasc Endovascular Surg

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Background and purpose: Stenting appears to be a safe treatment for vertebral artery ostial stenosis (VAOS) with low complication rates and positive long-term effects. However, in-stent restenosis (ISR) after stenting is common. Drug-coated balloons (DCBs) are an effective management strategy for ISR in patients with coronary or carotid disease. In this study, we investigated the feasibility, safety, and effectiveness of DCB-assisted angioplasty for the treatment of ISR after treatment of VAOS. Research Design: The study included patients in the Department of Neurology at Beijing Tsinghua Changgung Hospital who underwent DCB-assisted angioplasty for ISR after previously undergoing stenting for VAOS. We retrospectively analyzed the clinical and functional outcomes in these patients. Results: Fourteen patients were enrolled in the study between January 2018 and April 2022. Five of the patients were female, and the mean age was 69.4 ± 7.5 years. The technical success rate was 100% and the mean operation time was 57.1 ± 29.2 minutes. No perioperative complications were reported. There were no new cases of cerebral infarction or transient ischemic attacks in hospital or during 6 months of follow-up. There were only 2 reports of ISR in the vertebral artery ostium in the 6 months following DCB-assisted angioplasty. The median modified Rankin scale score was 0. Conclusion: DCB-assisted angioplasty may be feasible for treatment of ISR after stenting of the vertebral artery ostium. However, more research is needed to confirm our findings.

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Treatment of In-stent Restenosis of the Internal Carotid Artery Using Drug-eluting Balloons

Cited by 2 publications

References 25 publications

Rapid-Test Kit for Cardiac Troponin I: A Reliable Enzyme-Linked-Immuno-Substrate-Assay-Based Biosensor for Daily-Use Naked-Eye Detection and Pharmacokinetic Studies for Myocardial Infarction in Cardiovascular Disease

Rapid-Test Kit for Cardiac Troponin I: A Reliable Enzyme-Linked-Immuno-Substrate-Assay-Based Biosensor for Daily-Use Naked-Eye Detection and Pharmacokinetic Studies for Myocardial Infarction in Cardiovascular Disease

Drug-Coated Balloon Angioplasty for In-Stent Restenosis in the Vertebral Artery Ostium: Experiences From a Single Center

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