Treatment of Ingrown Toenail

Dixon, George L.

doi:10.1177/107110078300300503

Cited by 18 publications

(8 citation statements)

References 15 publications

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“…Resolution of gene pathways through methylome analysis was accomplished by incorporating dcl2 , dcl3 , and dcl4 mutants to identify siRNA-dependent methylation variation. The approach was coupled with high resolution methylation analysis by the Methyl-IT platform 65 . As in earlier studies of msh1 mutant and memory effects 16 , and in other biological systems 66 , integration of gene expression and methylome data provided greater resolution than either dataset alone.…”

Section: Discussionmentioning

confidence: 99%

MSH1-induced heritable enhanced growth vigor through grafting is associated with the RdDM pathway in plants

et al. 2020

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Plants transmit signals long distances, as evidenced in grafting experiments that create distinct rootstock-scion junctions. Noncoding small RNA is a signaling molecule that is graft transmissible, participating in RNA-directed DNA methylation; but the meiotic transmissibility of graft-mediated epigenetic changes remains unclear. Here, we exploit the MSH1 system in Arabidopsis and tomato to introduce rootstock epigenetic variation to grafting experiments. Introducing mutations dcl2, dcl3 and dcl4 to the msh1 rootstock disrupts siRNA production and reveals RdDM targets of methylation repatterning. Progeny from grafting experiments show enhanced growth vigor relative to controls. This heritable enhancement-through-grafting phenotype is RdDM-dependent, involving 1380 differentially methylated genes, many within auxin-related gene pathways. Growth vigor is associated with robust root growth of msh1 graft progeny, a phenotype associated with auxin transport based on inhibitor assays. Large-scale field experiments show msh1 grafting effects on tomato plant performance, heritable over five generations, demonstrating the agricultural potential of epigenetic variation.

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Section: Discussionmentioning

confidence: 99%

MSH1-induced heritable enhanced growth vigor through grafting is associated with the RdDM pathway in plants

et al. 2020

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“…[5][6][7][8][9][10] Patients must keep the device until the nail grows over the nail fold. This procedure is valid only in stage 1 disease and requires patient cooperation.…”

Section: Discussionmentioning

confidence: 99%

Wedge Excision of the Nail Fold in the Treatment of Ingrown Toenail

Persichetti

Simone

Vecchi

et al. 2004

Annals of Plastic Surgery

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Many treatment modalities of ingrown toenail are reported in the literature, often associated with unacceptably high recurrence rate. The authors present their technique, which aims at reducing the convexity of the nail fold. After complete removal of the nail plate and accurate debridement of the granulomatous tissue, a wedge-shaped ellipsis of skin and subcutaneous tissue, lateral to the affected nail fold, is removed. Approximation of the margins of the resulting defect determines eversion of the nail fold. One hundred twenty ingrown toenails were treated with the wedge excision of the nail fold at the outpatient clinic of the department of plastic surgery, Campus Bio-Medico University, Rome, Italy, between January 1998 and January 2002. Six recurrences were observed. In addition to the high cure rate, short postoperative pain duration, and morbidity as well as low risk of postoperative infection, the remarkable esthetic results achievable with this method are indicated.

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“…The clinical presentation of ingrown nails was divided into three stages (Fig. ) . Following the procedure, we checked the presence of pain and the shape of the nail during every visit.…”

Section: Methodsmentioning

confidence: 99%

“…2). 5 Following the procedure, we checked the presence of pain and the shape of the nail during every visit.…”

Section: Methodsmentioning

confidence: 99%

Treatment of ingrown nail with a special device composed of shape‐memory alloy

Park

Lee

et al. 2014

The Journal of Dermatology

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Ingrown nail is a common nail problem resulting in pain and disability in daily life. Recently, a new treatment modality for an ingrown nail was reported that used a device composed of shape-memory alloy, K-D. The aim of the present study was to determine the efficacy, recurrence rate and complications of K-D. Between June 2010 and September 2012, 24 patients (31 nails) underwent treatment of symptomatic incurved nails with a K-D. Patients were evaluated at pretreatment and during every visit. The mean age of the patients involved was 43.4 years. The mean period of follow up was 161 days. The mean maintenance period was 41 days. The right first toenail was the most common site. Almost ingrown nails healed and the nail deformity was corrected after the procedure. Among the 31 nails, seven of the ingrown nails recurred during follow up (22.6% recurrence rate). The recurrence rate of the patients with stage 1, 2 and 3 ingrown nails was 22.2%, 33.3% and 14.2%, respectively. The majority of patients were very satisfied. There were no side-effects in most patients except loss of nail in one patient. K-D has some advantages such as simple application steps, no deformity after the procedure, high patient satisfaction and obvious effect compared to other non-invasive and invasive methods.

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Treatment of Ingrown Toenail

Cited by 18 publications

References 15 publications

MSH1-induced heritable enhanced growth vigor through grafting is associated with the RdDM pathway in plants

MSH1-induced heritable enhanced growth vigor through grafting is associated with the RdDM pathway in plants

Wedge Excision of the Nail Fold in the Treatment of Ingrown Toenail

Treatment of ingrown nail with a special device composed of shape‐memory alloy

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