“…Longer pulse-durations in the 40-50 milliseconds domain are necessary to remove these linear vessels without vessel rupture and resulting purpura that can last 7-14 days following treatment [1][2][3][4]. Until recently, only the KTP laser offered highly-effective, selective, purpura-free removal of these vessels.…”
The high-energy, long pulse-duration pulsed-dye laser improves rosacea with a very favorable safety profile, and less purpura than resulted from earlier generation pulsed-dye lasers.
“…Longer pulse-durations in the 40-50 milliseconds domain are necessary to remove these linear vessels without vessel rupture and resulting purpura that can last 7-14 days following treatment [1][2][3][4]. Until recently, only the KTP laser offered highly-effective, selective, purpura-free removal of these vessels.…”
The high-energy, long pulse-duration pulsed-dye laser improves rosacea with a very favorable safety profile, and less purpura than resulted from earlier generation pulsed-dye lasers.
“…Clearance rates among subjects have varied considerably, with many subjects having PWSs after as many as 10-25 treatments [5]. The development of a tunable PDL with a 1.5-millisecond pulse-duration, offers potential advantages for treating PWSs over conventional PDLs, with their shorter 0.5-millisecond pulse-duration [6][7][8]. We have previously reported a subject with a PWS that had become refractory to the 0.5-millisecond pulse-duration PDL.…”
“…Clearance averaged approximately 65-75%, when objectively measured by the treating physician, and approximately 40-50% as measured by blinded observers rating digital images. With longer follow-up, further clearance of veins should occur even without additional treatment [5,11] Subjective physician assessments and blinded analysis of vessel clearance differed by approximately 25%. This difference may be due to observer bias, or conversely, to the ability of the digital photographs to capture the images of some of the smallest veins.…”
Section: Discussionmentioning
confidence: 99%
“…It was later determined that 585 nm resulted in more effective treatment of PWSs [3]. Linear telangiectasias of the face and legs, rosacea, and scars responded better to 595 nm [4][5][6], presumably due to the ability of this wavelength to penetrate through the entire target vessel due to its decreased hemoglobin absorption as compared to 585 nm. In addition, due to the relatively large size of the lower-extremity spider veins as compared to facial veins or most vessels in PWSs, pulsedurations longer than the conventional 0.45-1.5 milliseconds were considered optimal for removing leg veins [6][7][8].…”
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