Treatment of lower lip cancer: an experience of 48 cases

Strukturierte Versorgung von Lippendefekten

“…Der erste Kasten entspricht bei der unilatera len Treppenplastik der Defektbreite, bei der bilateralen Treppenplastik der hal ben. Die Kästen werden von Stufe zu Stufe kleiner, um in einem kleinen BurowDrei eck auszulaufen [17,23]. Für zentrale De fekte eignet sich die bilaterale, für laterale die unilaterale Treppenplastik.…”

Distant bone metastases from carcinoma of the lip: a report of four cases

“…Lip carcinoma is considered to be a slowly growing, locally advancing disease. During the disease course, 3-29% of patients show regional lymph-node metastasis, a rate appearing low compared to other types of head and neck cancer 10,22 . It should be noted that upper lip and commissure carcinoma, although rarer, is less well differentiated, with earlier and more diffuse lymphatic metastasis (e.g.…”

“…Metastasis to bone and axillary lymph nodes is exceptionally rare and can be attributed to either inadequate initial management or aggressive tumour behaviour. The lip is a frequent site of presentation of head and neck cancer 7,23 , accounting for 30% of oral cavity carcinomas and 2.06% of all malignancies 10,22 . The prominent anatomical position of the lip aids early diagnosis and management.…”

“…The prominent anatomical position of the lip aids early diagnosis and management. Of these tumours, 80% occur in the lower lip, 5-8% in the upper lip and 7-15% in the commissures 22 . Carcinoma of the lip is significantly more frequent in men (80-90%) and especially in those with longstanding exposure to sunlight, such as farmers, builders and mariners, with incidence peaking in the 7th and 8th decades 5,22 .…”

Proteínas e polimorfismos de genes de reparo de DNA na fotocarcinogênese em lábio

“…. Além disso, metástases são observadas em torno de 3 a 29% dos casos, tendem a ocorrer para os linfonodos submentonianos e submaxilares mas geralmente estão associadas com lesões maiores que 3 mm 7,11,12,13,14 . Esta taxa varia de acordo com o grau de diferenciação histopatológico.…”