Treatment of Melasma with low fluence, large spot size, 1064-nm Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) laser for the treatment of melasma in Fitzpatrick skin types II–IV

Brown, Alia S; Hussain, Mussarat; Goldberg, David J.

doi:10.3109/14764172.2011.630084

Cited by 35 publications

(30 citation statements)

References 10 publications

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“…Most data studies shown that five treatment sessions, with intervals of 1–2 weeks, are the minimum necessary (range 5–12) for low‐fluence QSNY laser to treat melasma in Asian patients effectively . In contrast, some patients in our cohort achieved clinical improvement of greater than 75% after only two laser treatment sessions spaced at 4‐weeks intervals.…”

Section: Discussionmentioning

confidence: 73%

Oral Tranexamic Acid Enhances the Efficacy of Low-Fluence 1064-Nm Quality-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser Treatment for Melasma in Koreans: A Randomized, Prospective Trial

Shin

Park

et al. 2013

Dermatologic Surgery

106

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Section: Discussionmentioning

confidence: 73%

Oral Tranexamic Acid Enhances the Efficacy of Low-Fluence 1064-Nm Quality-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser Treatment for Melasma in Koreans: A Randomized, Prospective Trial

Shin

Park

et al. 2013

Dermatologic Surgery

106

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“…Although it could not be proved statistically due to the nature of uncontrolled study, it showed that roughly 10 treatments are needed to achieve satisfying results. Moreover, there is increasing evidence that low‐fluence QSNY is effective and safe for melasma . Lee et al treated 50 patients with melasma using QSNY (RevLite®; HOYA ConBio, CA, USA) at a fluence of 2.8 J/cm 2 weekly for 15 weeks, with 50%‐74% improvement and no serious side effects .…”

Section: Discussionmentioning

confidence: 99%

“…This involves multiple passes of a low‐fluence, collimated beam with a large spot size at a frequency of 5‐10 Hz and multiple weekly treatments. Low‐fluence QSNY reportedly improves melasma efficiently without significant adverse events and has been accepted as the new gold standard for melasma treatment in Asia …”

Section: Introductionmentioning

confidence: 99%

Low‐fluence Q‐switched Nd:YAG laser for the treatment of melasma in Asian patients

Choi

Lee

Seo

et al. 2018

J of Cosmetic Dermatology

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Background: Melasma is a common acquired facial pigmentary disorder that is resistant to various modalities of treatment. Recently, the low-fluence 1064-nm Qswitched neodymium-doped yttrium aluminum garnet laser (QSNY) has emerged as the new gold standard of melasma treatment in Asia. Objective: To evaluate the efficacy and safety of low-fluence 1064-nm QSNY in Asian patients with melasma. Methods: Data of patients with melasma treated with low-fluence QSNY in the department of dermatology at the Korea University Anam Hospital were reviewed retrospectively. A 1064-nm QSNY with 8 mm spot size and fluence of 1.2-2.0 J/cm 2 at 10 Hz was used. The results were evaluated using the modified Melasma Area and Severity Index (mMASI) score and the physician's global assessment (PGA).Results: A total of 40 Korean patients with Fitzpatrick skin type III to IV were included. Patients were treated for a median of 10 sessions at a median of 1-week intervals. The mean mMASI score decreased by 54.23% from a baseline of 3.19 ± 2.64 to 1.46 ± 1.06 after treatment. On PGA, 1 out of 40 patients (2.5%) showed excellent improvement, 14 (35%) good, 15 (37.5%) fair, 6 (15%) poor, and 4 (10%) no improvement. However, two patients showed mottled hypopigmentation and rebound hyperpigmentation. Conclusion:Low-fluence 1064-nm QSNY appears to be a safe and effective treatment for Asian patients with melasma.

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“…Various studies[18–27] done with this laser are summarized in Table 1. The fluence used is less than 5 J/cm 2 , spot size 6 mm, and frequency of 10 Hz.…”

Section: Q S Nd:yagmentioning

confidence: 99%

Lasers for treatment of melasma and post-inflammatory hyperpigmentation

Arora

Sarkar

Garg³

et al. 2012

J Cutan Aesthet Surg

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Hyperpigmentary disorders, especially melasma and post-inflammatory hyperpigmentation (PIH), cause significant social and emotional stress to the patients. Although many treatment modalities have been developed for melasma and PIH, its management still remains a challenge due to its recurrent and refractory nature. With the advent of laser technology, the treatment options have increased especially for dermal or mixed melasma. To review the literature on the use of cutaneous lasers for melasma and PIH. We carried out a PubMed search using following terms “lasers, IPL, melasma, PIH”. We cited the use of various lasers to treat melasma and PIH, including Q-switched Nd:YAG, Q-switched alexandrite, pulsed dye laser, and various fractional lasers. We describe the efficacy and safety of these lasers for the treatment of hyperpigmentation. Choosing the appropriate laser and the correct settings is vital in the treatment of melasma. The use of latter should be restricted to cases unresponsive to topical therapy or chemical peels. Appropriate maintenance therapy should be selected to avoid relapse of melasma.

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Treatment of Melasma with low fluence, large spot size, 1064-nm Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) laser for the treatment of melasma in Fitzpatrick skin types II–IV

Cited by 35 publications

References 10 publications

Oral Tranexamic Acid Enhances the Efficacy of Low-Fluence 1064-Nm Quality-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser Treatment for Melasma in Koreans: A Randomized, Prospective Trial

Oral Tranexamic Acid Enhances the Efficacy of Low-Fluence 1064-Nm Quality-Switched Neodymium-Doped Yttrium Aluminum Garnet Laser Treatment for Melasma in Koreans: A Randomized, Prospective Trial

Low‐fluence Q‐switched Nd:YAG laser for the treatment of melasma in Asian patients

Lasers for treatment of melasma and post-inflammatory hyperpigmentation

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