Treatment of migraine: update on new therapies

Magis, Delphine; Schoenen, Jean

doi:10.1097/wco.0b013e3283462c3f

Cited by 40 publications

(32 citation statements)

References 60 publications

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“…Occipital nerve stimulation is a neuromodulation technique currently under study to treat various migraine headache disorders [90]. In 12 patients sharing migraine and FM, the C2 area stimulation technique resulted in a global improvement of pain and associated symptoms [47].…”

Section: Nonpharmacological Approachesmentioning

confidence: 99%

“…The analgesic effects induced by neurostimulation of the motor cortex have shown efficacy in FM [85,86], while the effects induced by dorsolateral prewhile the effects induced by dorsolateral prefrontal cortex modulation are quite uncertain [87]. No data are available on the possible efficacy in patients sharing FM and chronic headache, although the positive effects on psychiatric symptoms of right and left dorsolateral prefrontal cortex neuromodulation may support its potential efficacy on factors favoring comorbidity [88,89].Occipital nerve stimulation is a neuromodulation technique currently under study to treat various migraine headache disorders [90]. In 12 patients sharing migraine and FM, the C2 area stimulation technique resulted in a global improvement of pain and associated symptoms [47].…”

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confidence: 99%

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Prevalence, clinical features and potential therapies for fibromyalgia in primary headaches

Tommaso

2012

Expert Review of Neurotherapeutics

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Fibromyalgia (FM) syndrome is predominantly related to generation and persistence of central sensitization, which is an aggravating factor for chronic headaches. This review aims to examine the last 11 years of studies on FM and primary headache comorbidity, focusing on prevalence, clinical features and treatments. Chronic forms of migraine and tension-type headache show a high frequency of FM comorbidity. The symptoms characterizing headache patients presenting with FM comorbidity are high headache frequency, poor sleep quality, pericranial tenderness, anxiety and reduction of physical performances. The effects of headache-preventive drugs on factors favoring FM comorbidity were poorly evaluated. Nonpharmacological approaches such as transcranial magnetic stimulation may be an option for treatment of chronic migraine associated with FM. Keywords: fibromyalgia • migraine • tension-type headache • therapeutic optionsPrevalence, clinical features and potential therapies for fibromyalgia in primary headaches Expert Rev. Neurother. 12(3), 287-296 (2012) THeMed ArTICLe y Migraine & Headache Learning objectivesUpon completion of this activity, participants will be able to:• Describe the prevalence and underlying pathophysiology of FM comorbid with headache • Describe the clinical characteristics of FM comorbid with headache • Describe available treatments for FM comorbid with headache Medscape: Continuing Medical Education OnlineThis activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of Medscape, LLC and Expert Reviews Ltd. Medscape, LLC is accredited by the ACCME to provide continuing medical education for physicians.Medscape, LLC designates this Journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.All other clinicians completing this activity will be issued a certificate of participation. To participate in this journal CME activity: (1) review the learning objectives and author disclosures; (2) study the education content; (3) take the post-test with a 70% minimum passing score and complete the evaluation at http://www.medscape.org/journal/expertneurothera; (4) view/print certificate. For reprint orders, please contact reprints@expert-reviews.com CME Expert Rev. Neurother. 12(3), (2012) 288 Review Possible causes of comorbidity between fibromyalgia & primary headachesFibromyalgia (FM) is a chronic pain syndrome of unknown etiology characterized by diffuse pain over more than 3 months and tenderness in at least 11 tender point sites out of 18 [1]. The diagnostic criteria have recently been revised in view of the full consideration of the complexity of symptoms associated with generalized pain, including nonrestorative sleep, fatigue and cognitive dysfunction, with less importance attributed to the number of painful tender points [2].The causes of F...

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Section: Nonpharmacological Approachesmentioning

confidence: 99%

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confidence: 99%

Prevalence, clinical features and potential therapies for fibromyalgia in primary headaches

Tommaso

2012

Expert Review of Neurotherapeutics

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“…Intravenous (IV) ketorolac can be used for emergency management of migraine. NSAID's needs to us be used with caution in patients with renal toxicity [26][27][28][29]. Characterized of different NSAID's are summarized in Table 3.…”

Section: Nsaidsmentioning

confidence: 99%

A Complete Review of Migraine

Ommurugan

Priya

Bairy

2017

Asian J Pharm Clin Res

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Migraine characterized by recurrent headaches present with aura or without aura. Various treatment modalities ranging from 5-hydroxytryptamine 1B/1D agonists, non-steroidal anti-inflammatory drugs to steroids are available for acute treatment of migraine. Prophylaxis for chronic cases is usually with β blockers, calcium channel blockers, and antiepileptics. Even many nutraceutical preparations are helpful in migraine including riboflavin, vitamin b12. This review focuses on the newer agents available for treatment of migraine with some sight into their clinical trials.

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“…One-third of migraine sufferers usually have three or more attacks per month. These patients need to bed rest and their daily activities limit, so the prophylactic treatment is very important (1,2). The important classes of drugs for migraine prophylaxis are beta-blocker, calcium channel blockers, tricyclic antidepressants and anticonvulsants.…”

Section: Introductionmentioning

confidence: 99%

“…Calcium channel blockers prevent intracellular calcium entry. Tricyclic antidepressants act as reuptake of serotonin inhibitors at central sites (2)(3)(4). The drugs for migraine prophylaxis are not completely effective or safe (3).…”

Section: Introductionmentioning

confidence: 99%

The Effect of Feverfew Cultivated in Iran for the Prophylactic Treatment of Migraine: A Randomized Placebo-controlled Clinical Trial

Rafie

Namjoyan

Hassanzadeh

et al. 2015

Jundishapur J Nat Pharm Prod

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Background: One of the most common types of headache is migraine that often begins before 30 years age. The use of complementary preventive treatments has been growing worldwide that can be decrease the frequency and severity of migraine attacks with minimal side effects. Tanacetum parthenium L. (common name: feverfew) from Compositae family have traditionally been used as a febrifuge and remedy for migraine prophylaxis. Objectives: In present study, the effect of feverfew cultivated in Iran has been studied as a prophylactic treatment of migraine in a placebocontrolled clinical trial during 3 months. Patients and Methods: Criteria for inclusion were migraine without aura diagnosed after a careful medical history-taking according to the International Headache Society (IHS) criteria. The Migraine Disability Assessment Scores (MIDAS) questionnaire is quite a useful tool in clinical trial that the patients were recognized for migraine impact at the baseline and end of the study. Results: In the case group, after three months of treatment with feverfew, the MIDAS score was reduced to 19.18 ± 4.02. Compared to control group, the changes in intensity and frequency of migraine, in the treatment group was significant, at the end of the study (P < 0.05). Regarding the safety of feverfew extract the incidence of side effects in the treatment group was similar to placebo. Conclusions: In conclusion, the extract of feverfew showed a significant migraine prophylactic effect with no adverse events.

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Treatment of migraine: update on new therapies

Abstract: Drugs with a better efficacy or side-effect profile than triptans may soon become available for acute treatment. The future may also look brighter for some of the very disabled chronic migraineurs thanks to novel drug and neuromodulation therapies.

Cited by 40 publications

References 60 publications

Prevalence, clinical features and potential therapies for fibromyalgia in primary headaches

Prevalence, clinical features and potential therapies for fibromyalgia in primary headaches

A Complete Review of Migraine

The Effect of Feverfew Cultivated in Iran for the Prophylactic Treatment of Migraine: A Randomized Placebo-controlled Clinical Trial

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