Treatment of Mild to Moderate Obesity with Laparoscopic Adjustable Gastric Banding or an Intensive Medical Program

O'Brien, Paul Edmond; Dixon, John; Laurie, Cheryl; Skinner, Stewart; Proietto, Joseph; McNeil, John J; Strauss, Boyd Josef Gimnicher; Marks, Sharon; Schachter, Linda M.; Chapman, Leon; Anderson, M. Robin

doi:10.7326/0003-4819-144-9-200605020-00005

Cited by 467 publications

(396 citation statements)

References 24 publications

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“…[34][35][36][37][38][39][40][41][42] The largest adolescent series to date is also Australian, consisting of 41 adolescents (age range 12-19 years) with a mean weight of 125 kg, and a mean BMI 42 kg/m 2 . 43 These patients generally presented without any major physical health problem associated with obesity, with the exception of five patients with either T2DM, OSAS or hypertension.…”

Section: The Modern Era Of Bariatric Surgical Procedures For Adolescentsmentioning

confidence: 99%

Bariatric surgery for pediatric extreme obesity: now or later?

2006

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Obesity is a multifactorial disease of epidemic and global proportions that poses the most significant threat to the health of our younger generations. Those who are the most extremely affected bear the largest burden of health problems. In the US, extreme obesity affects approximately 9 million adults and 2 million children, and is associated with both immediate health problems and later health risk, including premature mortality. Present medical and behavioral interventions for extreme obesity in adults and children rarely result in the significant, durable weight loss necessary to improve health outcomes, prompting a search for more aggressive measures. Weight loss (bariatric) surgery has been advocated as an intervention for those with extreme obesity. In adults, bariatric surgery results in prolonged weight control and improvement in serious obesity comorbidities, namely type 2 diabetes, dyslipidemias, hypertension and obstructive sleep apnea syndrome. A surge in weight loss operations for adolescents has been observed recently, with a threefold increase in case volumes nationwide from 2000 to 2003. Current evidence suggests that after bariatric surgery, adolescents lose significant weight and serious obesity-related medical conditions and psychosocial status are improved. Thus it is reasonable to propose that bariatric surgery performed in the adolescent period may be more effective treatment for childhood-onset extreme obesity than delaying surgery for extremely obese youth until adulthood. This position has been echoed by a number of groups and an independent systematic review. Finally, it is conceivable that bariatric surgery performed in adulthood for childhood onset extreme obesity may not be as effective for comorbidity treatment as surgery performed earlier during adolescence. The purpose of this review is to examine the evidence, which supports early rather than later use of bariatric surgery in the treatment of extreme obesity, and to present this information in light of the medical and surgical risks of bariatric surgery.

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Section: The Modern Era Of Bariatric Surgical Procedures For Adolescentsmentioning

confidence: 99%

Bariatric surgery for pediatric extreme obesity: now or later?

2006

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“…6 Over a 6-month period 2025 patients admitted to New Mount Sinai Hospital, Toronto were screened for hepatitis B surface antigen (HBsAg) by counterimmunoelectrophoresis (CIEP) and radioimmunoassay (RIA). CIEP detected 12 HBsAg-positive patients and RIA 16. RIA is therefore the more sensitive test for HBsAg.…”

Section: Types Of Abstractsmentioning

confidence: 99%

Structured abstracts: narrative review

Guimarães

2006

Acta Cir. Bras.

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Purpose: To summarize the main findings from research on structured abstracts. Methods: A narrative review of all the relevant papers known to the author was conducted. Results: Authors and readers judged the structured abstracts to be more useful than traditional ones. In 1987 the Ad Hoc Working Group for Critical Appraisal of the Medical Literature proposed guidelines for informative seven-headings abstracts. In 1990 Haynes et al. reconsidered the structured abstract of clinical research and review articles and proposed revised guidelines. Nowadays, most abstracts are informative, and the most commonly used structure is IMRAD (Introduction, Methods, Results And Discussion) format. Conclusions: There are many variations in the structured-abstract formats prescribed by different journals. But even in recent years, not all abstracts of original articles are structured. More research is needed on a number of questions related to the quality and utility of structured abstracts. Key words: Abstracting and indexing. Review literature. Peer review RESUMO Objetivo: Sintetizar os principais resultados das pesquisas sobre resumos estruturados.. Métodos: Uma revisão narrativa de todos os estudos, considerados relevantes pelo autor, foi realizada. Resultados: Os autores e os leitores julgaram que os resumos estruturados são mais úteis que os tradicionais. Em 1987, o Ad Hoc Working Group for Critical Appraisal of the Medical Literature propôs diretrizes para a elaboração de resumos informativos com sete seções. Haynes e col., em 1990, reestudaram os resumos estruturados para a pesquisa clínica e para os artigos de revisão e propuseram novas diretrizes. Atualmente, a maioria dos resumos é informativa e a estrutura mais utilizada é aquela do formato IMRAD (Introdução, Métodos, Resultados e Discussão) Conclusão: Há muita variação nos formatos dos resumos estruturados solicitados pelo vários periódicos. Contudo, mesmo nos anos mais recentes, nem todos os resumos dos artigos originais são estruturados. Necessita-se de mais pesquisas relacionadas à qualidade e à utilidade dos resumos estruturados. Descritores: Resumos e indexação. Literatura de revisão. Comissão de avaliação de exercício profissional Types of abstractsSince its origin in 1665, the scientific paper has been through many changes, but method description only developed during the second half of the 19th century. In the course of the 20th century, the formal established Introduction, Methods, Results, And Discussion (IMRAD) structure was adopted. 1 The proposed structured abstract, that is, abstract that describe a study using content headings, provided more informative content. Except for the title, the abstract is the part of a scientific paper that will be read by the most people. 2 The basic purpose of abstracts is to summarize the contents of articles so that readers can decide whether to read them. It is the only part of an article that many journals will make accessible through search engines. 3 Indicative or descriptive abstracts deal with the content...

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“…In the current unabating overweight and obesity epidemic, bariatric surgery has been proven to be an effective therapeutic option for morbidly-obese carefully-selected patients with previous failure on conventional treatment (Buchwald et al 2004;Steinbrook, 2004;Crookes, 2006;Hansen et al 2006;O'Brien et al 2006). One of the effects of bariatric surgery is to enhance satiety and reduce subjective hunger.…”

Section: Ghrelin Changes Following Bariatric Surgerymentioning

confidence: 99%

The Sir David Cuthbertson Medal Lecture Hunting for new pieces to the complex puzzle of obesity

Frühbeck

2006

Proc. Nutr. Soc.

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Disentangling the neuroendocrine systems that regulate energy homeostasis and adiposity has been a long-standing challenge in pathophysiology, with obesity being an increasingly important public health problem. Adipose tissue is no longer considered a passive bystander in bodyweight regulation. It actively secretes a large number of hormones, growth factors, enzymes, cytokines, complement factors and matrix proteins, at the same time as expressing receptors for most of these elements, which influence fuel storage, mobilisation and utilisation at both central and peripheral sites. Thus, an extensive cross talk at a local and systemic level in response to specific external stimuli or metabolic changes underpins the multifunctional characteristics of adipose tissue. In addition to the already-known adipokines, such as IL, TNFa, leptin, resistin and adiponectin, more recently attention has been devoted to 'newcomers' to the 'adipose tissue arena', which include aquaporin, caveolin, visfatin, serum amyloid A and vascular endothelial growth factor. While in vitro and in vivo experiments have provided extremely valuable information, the advances in genomics, proteomics and metabolomics are offering a level of information not previously attainable to help unlock the molecular basis of obesity. The potential and power of combining pathophysiological observations with the wealth of information provided by the human genome, knock-out models, transgenesis, DNA microarrays, RNA silencing and other emerging technologies offer a new and unprecedented view of a complex disease, conferring novel insights into old questions by identifying new pieces to the unfinished jigsaw puzzle of obesity.

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Treatment of Mild to Moderate Obesity with Laparoscopic Adjustable Gastric Banding or an Intensive Medical Program

Abstract: Surgical treatment using laparoscopic adjustable gastric banding was statistically significantly more effective than nonsurgical therapy in reducing weight, resolving the metabolic syndrome, and improving quality of life during a 24-month treatment program.

Cited by 467 publications

References 24 publications

Bariatric surgery for pediatric extreme obesity: now or later?

Bariatric surgery for pediatric extreme obesity: now or later?

Structured abstracts: narrative review

The Sir David Cuthbertson Medal Lecture Hunting for new pieces to the complex puzzle of obesity

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