Treatment of nevoid hyperkeratosis of the areola and nipple with topical tacalcitol: A case report

Cinotti, Élisa; Provvidenziale, Luca; Miracco, Clelia; Rubegni, Pietro

doi:10.1111/dth.12602

Cited by 10 publications

(6 citation statements)

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“…Two nevoid hyperkeratosis revealed a papillomatous surface with pink homogenous areas, whitish desquamation, focal red dots and small erosions in one case and multiple blue‐grey globules and leaf‐like areas mimicking a pigmented BCC in the other one . Hyperkeratosis of the nipples induced by vemurafenib treatment showed multiple, angulated, whitish to brownish hyperkeratotic clods in five patients .…”

Section: Resultsmentioning

confidence: 95%

“…Two primary MMs, two nevi, PDs, melanoses, two BCCs, two nevoid hyperkeratosis, three adenomas/erosive adenomatosis of the nipple one eczema and five vemurafenib‐induced hyperkeratosis have been described in case reports. Most descriptions only concern dermoscopy, and only eight cases have been evaluated with RCM . Moreover, a large multicentric study evaluated 131 NAC lesions at clinical, dermoscopic and RCM examination and compared the diagnostic accuracy of these three examinations .…”

Section: Resultsmentioning

confidence: 99%

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Nipple and areola lesions: review of dermoscopy and reflectance confocal microscopy features

Cinotti

Galluccio

Tognetti

et al. 2019

Acad Dermatol Venereol

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The differential diagnosis of nipple and areola complex (NAC) lesions encompasses a large spectrum of conditions from benign tumours to inflammatory diseases that could be challenging to recognize on clinical ground. While melanoma (MM) of the NAC is exceedingly rare, benign lesions are more frequent but could be difficult to distinguish from MM.Besides MM, other malignant tumours can affect this area and in particular Paget's disease (PD). For clinically doubtful lesions, biopsy is required, with possible functional and aesthetic consequences in this sensitive area. Dermoscopy and reflectance confocal microscopy (RCM) are widely used techniques for the diagnosis of many skin lesions, but their use for NAC lesions is not well established. The objective of this study was to evaluate current literature on these imaging techniques for NAC lesions. We searched in Medline, PubMed and Cochrane database all studies up to November 2018 dealing with dermoscopy, RCM and this special site. We found that the most described malignant tumour was PD and that only three primary MMs of the NAC have been reported with these imaging techniques. Although there are few data on diagnostic accuracy of non-invasive imaging techniques for NAC lesions, it seems that dermoscopy and RCM can add relevant information to be integrated with clinical examination for the diagnosis of NAC lesions and in particular for the differential diagnosis of PD and eczema.

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Section: Resultsmentioning

confidence: 95%

Section: Resultsmentioning

confidence: 99%

Nipple and areola lesions: review of dermoscopy and reflectance confocal microscopy features

Cinotti

Galluccio

Tognetti

et al. 2019

Acad Dermatol Venereol

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“…Cinotti et al reported that at dermoscopic examination the NHNA showed a papillomatous surface with pink homogenous areas, whitish desquamation, red dots, and erosions [1].…”

Section: Discussionmentioning

confidence: 99%

Dermoscopic Features of Nevoid Hyperkeratosis of the Nipple and Areola

Conforti

Dri

Giuffrida

et al. 2022

Dermatol Pract Concept

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“…Drug therapies alone have great differences in effect and disease recurrence has been reported after discontinuation of most of these drugs. 6 Cryotherapy, radiofrequency ablation and fractional laser have been reported to have good results in individual cases. However, the recovery time may be long and the depth of treatment is difficult to control.…”

Section: Sirmentioning

confidence: 99%