Treatment of non-cirrhotic, non-tumoural portal vein thrombosis

Llop, Elba; Seijó, Susana

doi:10.1016/j.gastre.2015.09.001

Cited by 10 publications

(16 citation statements)

References 73 publications

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“…Nevertheless, PVT is the second most common cause of portal hypertension. 2 First, It is important to determine the cause of PVT, cirrhosis or non-cirrhosis then acute or chronic because it is related to the choice of therapy. AASLD recommends to diagnose chronic PVT in all patients with newly found portal hypertension, and acute PVT if there is abdominal pain for more than 24 hours, fever or ileus.…”

Section: Discussionmentioning

confidence: 99%

Non Cirrhotic Portal Vein Thrombosis: Diagnostic and Therapeutic Challenge

Mustika¹,

Krisna

2021

InaJGHE

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Portal vein thrombosis (PVT), the second most common cause of portal hypertension, can be found in cirrhosis and non-cirrhosis patients. Various factors can cause non-cirrhosis PVT, such as biliary infection. Upper gastrointestinal bleeding without sign of liver failure, must be considered as non-cirrhosis PVT manifestation. Combining physical, laboratory, endoscopic and radiological examination is needed to establish the diagnosis of PVT. The principle of PVT management consists of 3 keypoints. They are prevention and treatment of gastrointestinal bleeding, prevention of recurrent thrombosis and portal cholangiopathy therapy. Many aspect should be considered regarding the administration of anticoagulants in PVT patients, especially chronic PVT with cavernomas.

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Section: Discussionmentioning

confidence: 99%

Non Cirrhotic Portal Vein Thrombosis: Diagnostic and Therapeutic Challenge

Mustika¹,

Krisna

2021

InaJGHE

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“…Sin embargo, estas opciones son limitadas, puesto que hasta en el 50 % de los casos se ha observado trombosis de las venas esplénica y mesentérica superior. El procedimiento de Sugiura modificado surge entonces como una opción para estos pacientes (7,(9)(10)(11).…”

Section: Discussionunclassified

“…De cualquiera manera, no existen muchas investigaciones acerca del manejo del sangrado variceal en el contexto de esta patología. Las recomendaciones actuales se basan en datos de pacientes con hipertensión portal y cirrosis (7). Este estudio es una serie de casos de pacientes con trombosis portal extrahepática, realizado en aquellos no cirróticos con sangrado variceal recurrente, quienes fueron sometidos a la devascularización de Sugiura modificado.…”

Section: Introductionunclassified

Sugiura modificado: una alternativa para pacientes no-cirróticos con trombosis de la porta extrahepática y sangrado variceal recurrente

Juri

Castro-Villegas

Ocampo

2020

Rev Colomb Gastroenterol

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Una de las consecuencias más graves de la trombosis de la vena porta extrahepática es la hipertensión portal con sangrado variceal recurrente. Una vez falla la ligadura endoscópica de las várices y el eje esplenoportal no se encuentra permeable, la devascularización tipo Sugiura modificado puede ser la única alternativa. Se ha documentado su uso en pacientes con cirrosis, pero hay poca información en personas no cirróticas. En este artículo se describe una serie de 4 casos de pacientes no cirróticos, en los cuales se realizó dicho procedimiento. Los pacientes fueron seguidos durante 12 meses y ninguno presentó episodios de resangrado de las várices esofágicas, ni tampoco se requirió la ligadura de las várices residuales. Esta cirugía se perfila como una alternativa terapéutica para este tipo de pacientes.

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“…Portal vein thrombosis (PVT) is an occlusion of the portal vein with or without extension to the splanchnic venous system. PVT can be acute or chronic, and accurate management of PVT depends on the underlying cause identified [1]. Entities that can cause PVT include cirrhosis or tumoral invasion, or extrinsic compression from a tumor.…”

Section: Introductionmentioning

confidence: 99%

Portal Vein Thrombosis in a Patient With Methylenetetrahydrofolate Reductase Gene Mutation and Normal Homocysteine Levels

Ghumman¹,

Ishtiaq²,

Avasthi³

2021

Cureus

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A 21-year-old male presented with chief complaints of abdominal pain, nausea, and vomiting and was found to have portal vein thrombosis (PVT) on computed tomography (CT) scan of the abdomen, which was redemonstrated on ultrasound. Thrombophilia workup was negative except that patient was heterozygous for methylenetetrahydrofolate reductase (MTHFR) gene mutation. Homocysteine levels were normal. The patient was started on enoxaparin and discharged on apixaban with the plan to continue anticoagulation for at least six months. Follow-up MRI after four months showed interval improvement of the main portal vein thrombus with the use of Eliquis.

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Treatment of non-cirrhotic, non-tumoural portal vein thrombosis

Cited by 10 publications

References 73 publications

Non Cirrhotic Portal Vein Thrombosis: Diagnostic and Therapeutic Challenge

Non Cirrhotic Portal Vein Thrombosis: Diagnostic and Therapeutic Challenge

Sugiura modificado: una alternativa para pacientes no-cirróticos con trombosis de la porta extrahepática y sangrado variceal recurrente

Portal Vein Thrombosis in a Patient With Methylenetetrahydrofolate Reductase Gene Mutation and Normal Homocysteine Levels

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