Treatment of obstructive sleep apnea syndrome with a Kampo‐formula, San’o‐shashin‐to: A case report

Hisanaga, Akito; Saitoh, Osamu; Fukuda, Hidemichi; Kurokawa, Kenzo; Okabe, Akihito; Tachibana, Hideki; Hagino, Hirofumi; Mita, Tatsuo; Yamashita, Iwao; Tsutsumi, Manabu; Kurachi, Masayoshi; Itoh, Takashi

doi:10.1046/j.1440-1819.1999.00512.x

Psychiatry Clin Neurosci

1999

DOI: 10.1046/j.1440-1819.1999.00512.x

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Treatment of obstructive sleep apnea syndrome with a Kampo‐formula, San’o‐shashin‐to: A case report

Akito Hisanaga

Osamu Saitoh

Hidemichi Fukuda³

et al.

Abstract: The following describes a 76-year-old male with obstructive sleep apnea syndrome successfully treated with a Kampo-formula, San'o-shashin-to (Formula medicamentorum tres ad dispellendi cordis). Polysomnography, performed before and after administration of San'o-shashin-to, revealed that the apnea index decreased from 11.1 events/hour to 4.1 events/hour, and that the apnea plus hypopnea index decreased from 18.4 events/hour to 10.7 events/hour. The patient was normo-weight (body mass index: 20.4 kg/m 2 ), and e… Show more

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Cited by 4 publications

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“…Scattered reports of herbal and pharmacological approaches have been published. [4][5][6] Didgeridoo training has been reported to improve OSAHS. 7 With this in mind, perhaps we should think twice before completely ruling out other physical training modalities as well.…”

mentioning

confidence: 99%

Emphasizing the Complementary in CAM

Eichling

2007

Journal of Clinical Sleep Medicine

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mentioning

confidence: 99%

Emphasizing the Complementary in CAM

Eichling

2007

Journal of Clinical Sleep Medicine

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Nonprescription Treatments of Snoring or Obstructive Sleep Apnea: an Evaluation of Products with Limited Scientific Evidence

Meoli

Rosen

Kristo

et al. 2003

Sleep

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Given the paucity and quality of scientific literature regarding the nonpharmacologic treatment of snoring and obstructive sleep apnea, members of the Clinical Practice Review Committee had insufficient information to develop standards of practice recommendations. Nevertheless, substantial publicity regarding such treatments is available to the general public. Very limited data are available to support a beneficial effect of these devices on snoring and minimal evidence is available to support their use in treating obstructive sleep apnea. Studies are limited by small numbers of participants and, in some instances, inadequate design, lack of statistical analysis, and sparse use of objective measurements. Many studies do not evaluate product safety, especially over extended use. Physicians may find this information useful in counseling their patients.

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Nasal Breath in the Lateral Position for Sleep Apnea: a Retrospective Case Series

Kim¹

2014

J Korean Med

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This was a retrospective case series about the clinical effect of integrated approach with behavior therapy for obstructive sleep apnea (OSA). Methods: Medical records of twelve patients with OSA who were treated with behavior modification including nasal breathing with oral appliances and sleep in lateral position, oral administration of herbal medicines and acupuncture treatment between January and September of 2013 were reviewed. Apnea-hypopnea index (AHI), day time sleepiness, apneas and hypopneas counts during sleep, risk indicator (RI), oxygen desaturation index, average saturation during sleep, lowest desaturation, lowest saturation, snoring events ratio and number of desaturations (%) were assessed before and after treatments with the ApneaLink device, which is a portable diagnostic apparatus for monitoring airflows of the patient's breath at home. Results: After an average 62.67 (SD 37.16) days of treatment, AHI (from 17.67, 12.79 to 8.75, 8.25, p=0.007), RI (from 22.00, 13.26 to 12.09, 8.03, p=0.004), oxygen desaturation index (from 17.33, 12.17 to 8.17, 7.86, p=0.005), and number of desaturations (from 7.00 times, 9.79 to 0.92 times, 1.39, p=0.044) showed significant improvement. Daytime sleepiness improved from 6.5 (3.2) to 3.8 (1.8) but there was no significant difference after treatment (p=0.17). No adverse events related to treatment were observed during participation in the treatment. Conclusion: From this case series, we found that behavior modification with herbal medication and acupuncture may be effective for improving sleep apnea without serious adverse events. Future randomized controlled trials with larger sample size will be necessary for concrete evidence on the benefit of this integrated treatment for OSA.

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Treatment of obstructive sleep apnea syndrome with a Kampo‐formula, San’o‐shashin‐to: A case report

Cited by 4 publications

References 2 publications

Emphasizing the Complementary in CAM

Emphasizing the Complementary in CAM

Nonprescription Treatments of Snoring or Obstructive Sleep Apnea: an Evaluation of Products with Limited Scientific Evidence

Nasal Breath in the Lateral Position for Sleep Apnea: a Retrospective Case Series

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