Treatment of odontogenic infections: An analysis of two antibiotic regimens

Bhagania, Manish Kumar; Youseff, Wael; Mehra, Pushkar; Figueroa, Ruben

doi:10.1016/j.jobcr.2018.04.006

Cited by 13 publications

(13 citation statements)

References 13 publications

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“…As infecções odontogênicas complexas são consideradas um problema sério de saúde pública 9 . As infecções que envolvem os espaços faciais profundos de cabeça e pescoço requerem internação hospitalar 10 , com custos elevados para o sistema de saúde.…”

Section: Discussionunclassified

Infecção cervicofacial grave de origem odontogênica – relato de caso

Rodrigues

Santos

Oliveira

et al. 2021

Rev. da Fac. de Odontologia, UPF

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Introdução: as infecções odontogênicas tem como principal origem a necrose pulpar com invasão bacteriana no tecido periapical e periodontal, podendo levar à formação de quadros de celulite e posteriormente de abscesso, além disso, possuem o potencial de disseminar-se pelos espaços faciais profundos e comprometer a vida do paciente. Complicações graves, decorrentes dos quadros de infecções odontogênicas, podem ocorrer, se o tratamento instituído não for adequado, como: trombose do seio cavernoso, abscesso cerebral, mediastinite e até óbito. Objetivo: discutir o manejo das infecções odontogênicas disseminados em espaços faciais profundos, através do relato de caso clínico. Caso clínico: paciente de 52 anos, portador de diabetes mellitus tipo 2, com infecção odontogênica, no exame clínico inicial apresentava trismo, disfonia, dispneia, disfagia, hiperemia e edema em lado esquerdo da face, envolvendo os espaços canino, bucal, submandibular e cervical além de unidades dentárias com foco infeccioso. Em exame de tomográfica computadorizada, observou-se desvio da via área, presença de um grande volume de gás e de lojas de infecção. Optou-se como tratamento a remoção dos focos dentários e drenagem intraoral foi realizada pela equipe da CTBMF com anestesia local e posteriormente drenagem sob anestesia geral, intubação com uso de fibroscopia pela equipe de cirurgia cabeça e pescoço. Considerações finais: as infecções odontogênicas que envolvem espaços faciais profundos devem ser tratadas com urgência e o tratamento de escolha dessa condição deve ser remoção imediata do foco infeccioso, exploração e drenagem rápida e agressiva dos espaços faciais envolvidos e associação com antimicrobianos de amplo espectro com características bactericidas.

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Section: Discussionunclassified

Infecção cervicofacial grave de origem odontogênica – relato de caso

Rodrigues

Santos

Oliveira

et al. 2021

Rev. da Fac. de Odontologia, UPF

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“…The obvious treatment for odontogenic cutaneous fistula is root canal treatment for recoverable teeth and removal of the source of infection by extracting teeth that are unrecoverable. The most effective empirical antibiotics to administer as a first-line treatment are clindamycin or a combination of penicillin and metronidazole [13].…”

Section: Discussionmentioning

confidence: 99%

A Case of Odontogenic Fistula Misdiagnosed as Cutaneous Ulcer on the Alar-Facial Angle

Kim

et al. 2020

J Wound Manag Res

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Odontogenic cutaneous fistula of dental origin at the alar-facial groove is rarely reported. As many patients present with only skin lesions without dental problems, it is often confused with a cyst, abscess or pyogenic granuloma. We report the case of a 52-year-old man who presented with a relapsing cutaneous ulcer in the left alar-facial groove area. Ultrasonography findings suggested a ruptured epidermal cyst, and an excisional biopsy was performed. At 10 days after the surgery, wound dehiscence and pus discharge were observed. Computed tomography revealed a sinus tract, and a diagnosis of odontogenic cutaneous fistula was made. After consultation with the dental department, endodontic treatment was performed. During reoperation, a remnant fistula from the left alar-facial groove area to the left upper central incisor was observed, for which fistulectomy was performed. The patient remained disease-free postoperatively. With early accurate diagnosis, patients with odontogenic cutaneous fistula can be protected from unnecessary surgical intervention and ineffective antibiotic therapy.

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“…Penicillin is also comparatively cheaper than other antibiotics. However, resistance has been reported against penicillins (17). Addition of a beta lactamase inhibitor such as clavulanic acid confers resistance against beta lactamases (18).…”

Section: Orofacial Infectionsmentioning

confidence: 99%

“…Metronidazole is also effective and it has activity against anaerobic organisms. It is often used in combination with a penicillin, cephalosporin or clindamycin (5,17). Clindamycin was prescribed in 13.2% of the cases.…”

Section: Orofacial Infectionsmentioning

confidence: 99%

Orofacial Infections in Kenya: A Retrospective Study

Mutwiri¹,

Dimba²,

Nzioka³

2021

Ann Afr Surg.

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Background: Orofacial infections are either odontogenic or non-odontogenic in nature. The clinical spectrum of these infections is diverse. This study aimed to describe the presentation and management of patients presenting with orofacial infections at Kenyatta National Hospital (KNH). Materials and Methods: This was a retrospective study based on clinical records of patients treated for orofacial bacterial infections at KNH fromJanuary 2016 to December 2018. Data on the following study variables were obtained and analyzed: demographic data, clinical presentation, diagnosis, management, and treatment outcome. Results: 214 clinical records were studied. Male to female ratio was 1.4:1 with age range of 3 months to 78 years (mean=27.0 years). Swelling (96.30%, n=206) was the most common symptom, next was pain (58.90%, n=123). The most common source of infection was odontogenic (60.30%,n=129) in nature. Permanent teeth (57.00%, n=122) were more commonly involved than deciduous teeth (2.80%, n=6). In both dentitions, the mandibular posterior teeth were the most commonly involved, Ludwig’s angina (30.84%, n=66) and submandibular abscess (25.23%, n=54) were the most common clinical diagnoses of orofacial bacterial infection. The commonly used treatment modality was a triad of extraction of the associated tooth, incision and drainage, and antibiotic therapy. These management modalities resulted in favorable treatment outcomes (92.50%, n=198) in most cases. Conclusion: Orofacial infections can occur among all sociodemographic groups. These infections are potentially life-threatening if not diagnosed early and managed promptly. Multidisciplinary teams are required to manage the severe morbidity and mortality of advanced orofacial infections. Keywords: Orofacial infections, Odontogenic, Abscess, Ludwig’s angina

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Treatment of odontogenic infections: An analysis of two antibiotic regimens

Abstract: Clindamycin alone and combination of Penicillin with Metronidazole are both effective pharmaceutical regimens for SOI. Clindamycin therapy resulted in shorter hospital stay and lower net treatment costs with a slightly higher success rate.

Cited by 13 publications

References 13 publications

Infecção cervicofacial grave de origem odontogênica – relato de caso

Infecção cervicofacial grave de origem odontogênica – relato de caso

A Case of Odontogenic Fistula Misdiagnosed as Cutaneous Ulcer on the Alar-Facial Angle

Orofacial Infections in Kenya: A Retrospective Study

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