Treatment of odontogenic keratocysts: A follow-up of 255 Chinese patients

Zhao, Yi‐Fang; Wei, Jinxiong; Wang, Shiping

doi:10.1067/moe.2001.125694

Cited by 159 publications

(168 citation statements)

References 25 publications

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“…In our case series, we found a male to female ratio was 2.2:1. We confirmed a male predominance of our clinical study, as reported previously (8,16,17,21,22).…”

Section: Discussionsupporting

confidence: 78%

“…In the presented study, KCOTs had a peak of occurance in the third decade of life, followed by the fifth decade. Most previous studies have noted a slight male dominance (5,8,16,17). Habibi et al (7) found in a Iranian population that males were affected more often than females.…”

Section: Discussionmentioning

confidence: 99%

“…The role of mutation of the PTCH gene in the etiology of KCOTs resulted in reclassification of this lesion as a neoplasm in the WHO classification of head and neck tumors in 2005 and its renaming as KCOT (5). KCOTs often occur in the mandibular ramus and angle region but rarely in other mandibular regions and in the maxillary region (7,8). Radiographically, KCOTs present as well defined radiolucent lesions with smooth and usually corticated margins.…”

Section: Introductionmentioning

confidence: 99%

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Keratokistik odontojenik tümör: 64 vakalık retrospektif çalışma

Akay¹,

Tetik²,

Zeytinoğlu³

2015

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Aim: The purpose of this retrospective study was to evaluate the clinicopathological features of 64 patients with keratocystic odontogenic tumor (KCOT). Materials and Methods:The patients ranged in age at the time of diagnosis from 8 to 74 years (mean: 38.20 ± 16.71). Postoperative follow-up period was 3-8 years (mean time 4.76 ± 1.10). This research was carried out on panoramic radiographs and histopathological samples. Data such as gender, age, treatment methods, location of the tumor, presence of impacted teeth and its histological features were subjected to descriptive statistical analyses with the statistical software program. Results:Of the 64 analyzed cases of KCOT, 68.8% of them were men and 31.2% were females (male-to-female ratio was 2.2:1). It was observed that KCOT peaked in the third and fifth decade of life (23.4%-20.3%). The incidence of KCOT was higher in the mandible than in the maxilla (76.6%-23.4%). There was recurrence in nine out of 64 subjects (14.1%) in the follow-up period. The recurrence was more often found in posterior mandible. It is noteworthy that in 9 recurrent subjects, 7 lesions were parakeratotic and 4 lesions were associated with daughter cysts. Conclusion:Although there are several studies about KCOT in the literature, the choice of treatment modalities remains controversial. In recurrent subjects, more aggressive therapy approaches should be considered. Periodic controls and aggressive treatment approaches may be effective in the prevention of recurrences. (%23.4-%20.3). KOT insidansı mandibulada maksillaya oranla daha yüksekti (% 76.6-% 23.4 Keywords

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“…In our case series, we found a male to female ratio was 2.2:1. We confirmed a male predominance of our clinical study, as reported previously (8,16,17,21,22).…”

Section: Discussionsupporting

confidence: 78%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Keratokistik odontojenik tümör: 64 vakalık retrospektif çalışma

Akay¹,

Tetik²,

Zeytinoğlu³

2015

Ege Tıp Dergisi

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“…Though it is accepted fact that the resection of the jaws results in the lowest recurrence rate, this procedure has also got highest morbidity. Even the enucleation with the application of Carnoy's solution can result in a recurrence rate comparable to that of resection without unnecessary aggressive treatment [6][7][8]. So unless resection is deemed necessary the most appropriate treatment would be enucleation of keratocyst and chemical cauterization with the Carnoy's solution.…”

Section: Discussionmentioning

confidence: 99%

“…Odontogenic keratocyst which was described by Philipsen in 1956 accounts for 3-10.5 % of all jaw cysts [5][6][7]. It is now designated by the world health organisation as a keratocystic odontogenic tumor (KCOT).Various treatment modalities for this lesion range from conservative methods like enucleation, curettage and marsupialisation to aggressive modalities like enucleation with adjunctive procedures like peripheral ostectomy, liquid nitrogen cryotherapy or application of Carnoy's solution and resection with or without loss of jaw continuity [5,[8][9][10].…”

Section: Discussionmentioning

confidence: 99%

Carnoy’s in Aggressive Lesions: Our Experience

Rajeshkumar

Kumar

Geetha

et al. 2012

J. Maxillofac. Oral Surg.

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Carnoy's solution is used in the treatment of various aggressive cysts and tumors in the maxillofacial region as a chemical cauterizing agent. Its use has been extensively studied in case of odontogenic keratocysts. It is used in the management of unicystic ameloblastomas and ossifying fibromas. In our institution from 2006 to 2010 we have treated 14 cases of maxillofacial lesions using carnoy's solution. Among these cases 7 were of odontogenic keratocyst, 4 cases were of amelobalstoma and one case was of juvenile ossifying fibroma. So here we share our experience of treating these lesions with the carnoy's solution.

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