“…Furthermore, a biochemical etiological component of the disease has also been identified [2], and the osteolytic activity of inflammatory metabolites produced by cystic tissue has been demonstrated. Nevertheless, in horses, SBCs are most commonly found in the medial condyle (MFC) of the femur, followed by phalanges, carpal bones, metacarpal and metatarsal bones, tibia, radius, talus, sesamoid bones, humerus, patella, and tarsal bones [3]. In general, both intermittent lameness and acute lameness can be observed soon after the onset of physical activity [4].…”