2020
DOI: 10.12659/msm.919166
|View full text |Cite
|
Sign up to set email alerts
|

Treatment of Osteoarthritis Secondary to Developmental Dysplasia of the Hip with Prolotherapy Injection versus a Supervised Progressive Exercise Control

Abstract: Departmental sources Background: Osteoarthritis secondary to developmental dysplasia of the hip (DDH) is one of the major causes of hip pain and disability. The aim of the study was to compare the effectiveness of prolotherapy (PrT) injections versus exercise protocol for the treatment of DDH. Material/Methods: There were 46 hips of 41 patients who had osteoarthritis secondary to DDH included in this study. Patients were divided into 2 groups: treated with PrT (PrT group; n=20) and exercise (control group; n=2… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
13
1
1

Year Published

2021
2021
2023
2023

Publication Types

Select...
6
2

Relationship

1
7

Authors

Journals

citations
Cited by 11 publications
(15 citation statements)
references
References 32 publications
0
13
1
1
Order By: Relevance
“…Concentrations up to 25% dextrose (hypertonic) have been used in most previous prolotherapy studies. In these studies, deep injections were applied to tendon-bone attachments, and healing was achieved by regenerative effects of hypertonic dextrose [ 44 47 ]. In these studies, some of the patients reported extreme pain, discomfort, and fatigue after the injections because of the inflammatory reaction arising from high concentrations of dextrose [ 40 , 48 ].…”
Section: Discussionmentioning
confidence: 99%
“…Concentrations up to 25% dextrose (hypertonic) have been used in most previous prolotherapy studies. In these studies, deep injections were applied to tendon-bone attachments, and healing was achieved by regenerative effects of hypertonic dextrose [ 44 47 ]. In these studies, some of the patients reported extreme pain, discomfort, and fatigue after the injections because of the inflammatory reaction arising from high concentrations of dextrose [ 40 , 48 ].…”
Section: Discussionmentioning
confidence: 99%
“…One study (9) had uncertain risk in terms of selection bias due to an unclear explanation of randomization and allocation process. Seven studies (10)(11)(12)(13)(14)(15)(16) were classified as high risk in terms of performance bias because there was no blinding for participants and these studies applied different techniques or treatments to the participants. Four studies (9,11,15,16) were classified as high risk in terms of detection bias because there was no blinding in the outcome assessor and the items of outcome likely to be influenced (ROM, deformity, and self-reported questionnaire).…”
Section: Risk Of Biasmentioning
confidence: 99%
“…Seven studies (10)(11)(12)(13)(14)(15)(16) were classified as high risk in terms of performance bias because there was no blinding for participants and these studies applied different techniques or treatments to the participants. Four studies (9,11,15,16) were classified as high risk in terms of detection bias because there was no blinding in the outcome assessor and the items of outcome likely to be influenced (ROM, deformity, and self-reported questionnaire). One study (14) was classified as high risk and 5 studies (3,9,15,17,18) were classified as an unclear risk in terms of attrition bias.…”
Section: Risk Of Biasmentioning
confidence: 99%
See 1 more Smart Citation
“…Estudios experimentales han documentado que las soluciones hiperosmolares como la solución salina y la dextrosa hipertónica protegen a los condrocitos de las lesiones mecánicas 4 y bloquean los receptores TRPV1, favoreciendo la reparación del tejido. Nuestro grupo de trabajo tiene particular experiencia con el uso de dextrosa hipertónica, con resultados similares a los documentados en este meta-análisis en red 5,6 respecto de la solución salina.…”
Section: Comentariounclassified