Treatment of Peri-implant Bone Defects with Platelet-Rich Fibrin

Abstract

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Regenerative potential of leucocyte‐ and platelet‐rich fibrin. Part B: sinus floor elevation, alveolar ridge preservation and implant therapy. A systematic review

“…2015, Öncü & Alaadinŏglu 2015) evaluated the benefits of the application of L‐PRF on the osseointegration process (Table 3). Öncü & Alaadinŏglu (2015) evaluated the impact of implant coating with L‐PRF.…”

“…Hamzacebi et al. (2015) assessed the effectiveness of the application of L‐PRF and conventional flap surgery for the treatment of peri‐implantitis bone loss. They reported more PD reduction (at 3 and 6 months: L‐PRF sites: 2.4 ± 1.1 mm and 2.8 ± 1.0 mm, non‐L‐PRF sites: 1.65 ± 1.0 mm and 2.0 ± 0.7 mm), and CAL gain (L‐PRF sites: 2.9 ± 1.0 mm, non‐L‐PRF sites: 1.4 ± 1.0 mm).…”

The use of platelet‐rich fibrin to enhance the outcomes of implant therapy: A systematic review

“…PRF increased the probing depth reduction, increased the gain in clinical attachment and reduced mucosal recession after 3 and 6 months (Hamzacebi et al., 2015). …”

“…One approach might be the use of PRF. Only one RCT, with a 6‐month follow‐up, observed the effect of PRF in peri‐implantitis defects (Hamzacebi et al., 2015). Although a significant improvement of pocket reduction, clinical attachment gain, and mucosal recession was found in the PRF group, it is not possible to draw a definitive conclusion.…”

Regenerative surgical treatment of peri‐implantitis using either a collagen membrane or concentrated growth factor: A 12‐month randomized clinical trial

“…Recently, Masuki et al21 stated that CGF and A-PRF have a similar capacity for inducing angiogenesis and subsequent wound healing/tissue regeneration, which is better than the results of platelet-rich plasma (PRP). A randomized, controlled, clinical trial evaluated the effect of PRF combined with flap surgery for the treatment of peri-implant bone loss and concluded that the additional use of PRF provided significant improvements in CAL gain 36. Moreover, it should be kept in mind that bone healing in intrabony periodontal defects is different from that of PBD due in particular to the differences in blood supply of the periodontium during the healing period.…”