Treatment of pityriasis amiantacea with infliximab

Pham, Ryan; Chan, C Stanley; Hsu, Sylvia

doi:10.5070/d35905b6kv

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Pityriasis amiantacea and folliculitis decalvans

2017

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We report on a 21-year-old woman with a 3-year history of crusts and erosions on her scalp that had appeared after starting treatment with adalimumab due to Crohn's disease. By clinicopathological correlation pityriasis amiantacea with underlying folliculitis decalvans was diagnosed. Topical and systemic antibiotic treatment showed rapid response. The occurrence of pityriasis amiantacea in folliculitis decalvans associated with tumor necrosis factor (TNF)-α inhibitor therapy is remarkable and highlights the ambivalent role of TNF-α in diseases with immunological dysfunctions in combination with infections.

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Pityriasis amiantacea and folliculitis decalvans

2017

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Therapeutic shampoos

Young¹,

Cooper²

2013

Comprehensive Dermatologic Drug Therapy

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Successful Use of Dupilumab for Treatment-resistant Pityriasis Amiantacea

Firsowicz¹,

Willenbrink²,

Shu³

et al. 2022

Journal of Dermatology and Dermatologic Surgery

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Pityriasis amiantacea (PA) is a scalp condition characterized by thick, adherent scales that are silvery or yellow–gray in color and bind down tufts of hair. PA is associated with several underlying dermatologic conditions including psoriasis, seborrheic dermatitis, atopic dermatitis, tinea capitis, pityriasis rosea, and Darier's disease. Although there is no consensus on standard treatment, PA is generally treated with keratolytic agents and/or ketoconazole shampoo. More resistant cases may require systemic therapies, including tumor necrosis factor-alpha inhibitors. We report a case of a 57-year-old female with severe PA resistant to numerous treatments including topical steroids, salicylic acid shampoo, intralesional steroid injections, mycophenolate mofetil, adalimumab, and apremilast. Following treatment with dupilumab, our patient experienced complete resolution of her PA. These results suggest that dupilumab may have in a role in the management of treatment-resistant PA, particularly when associated with eczematous dermatitis.

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Treatment of pityriasis amiantacea with infliximab

Cited by 5 publications

References 0 publications

Pityriasis amiantacea and folliculitis decalvans

Pityriasis amiantacea and folliculitis decalvans

Therapeutic shampoos

Successful Use of Dupilumab for Treatment-resistant Pityriasis Amiantacea

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