Treatment of Pneumatosis Cystoides Intestinalis With Oxygen

Gruenberg, James C.

doi:10.1001/archsurg.1977.01370010064012

Cited by 34 publications

(22 citation statements)

References 10 publications

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“…It was initially suggested that arterial oxygen concentrations in excess of 40 kPa (300 mm mercury) were necessary for resolution (Forgacs et al, 1973) but more recent experience, including that of the present series, suggests that lower concentrations are also effective (Gruenberg et al, 1977;Lee etal., 1977). Masks and nasal cannulae are more acceptable to patients, for oxygen tents are restricting and may result in a feeling of isolation for the patient (Lee et al, 1977).…”

Section: Discussionmentioning

confidence: 74%

“…Masks and nasal cannulae are more acceptable to patients, for oxygen tents are restricting and may result in a feeling of isolation for the patient (Lee et al, 1977). It would appear unnecessary to supplement inspired oxygen concentration during rest periods as suggested by Gruenberg et al, (1977), for we were able to discontinue therapy for short periods without any apparent prejudice to resolution of the disease.…”

Section: Discussionmentioning

confidence: 99%

“…It is the overall denitrogenation of the blood that occurs during the breathing of high concentrations of oxygen that leads to obliteration of the gas cysts. The net effect in pneumatosis coli is an alteration of the cyst capillary diffusion gradient in favour of absorption and resolution occurs (Forgacs et al, 1973;Gruenberg et a!., 1977).…”

Section: Discussionmentioning

confidence: 99%

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High flow oxygen therapy for pneumatosis coli.

Holt¹,

Gilmour²,

Buist³

et al. 1979

Gut

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Section: Discussionmentioning

confidence: 74%

Section: Discussionmentioning

confidence: 99%

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High flow oxygen therapy for pneumatosis coli.

Holt¹,

Gilmour²,

Buist³

et al. 1979

Gut

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“…In recent years attempts have been made to treat the few cases of symptomatic pneumatosis by oxygen breathing in order to facilitate diffusion of gas from the cysts [6,7]. The gas involves the mesentery and outlines the mesenteric blood vessels.…”

Section: Clinical Featuresmentioning

confidence: 99%

Pneumatosis cystoides coli

Marshak

Lindner

Maklansky

1977

Gastrointest Radiol

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images in clinical medicine T h e ne w e ngl a nd jou r na l o f m e dic i ne n engl j med 361;8 nejm.org august 20, 2009 e12 A 25-year-old woman presented with recurrent abdominal pain that had first developed 10 years earlier. Physical examination revealed mild tenderness in the left upper quadrant, without rebound or guarding. Laboratory tests showed no significant abnormalities. Coronal computed tomography (CT) (Panel A) and colonoscopy (Panel B, transverse colon) showed submucosal cysts confined to the splenic flexture and the distal transverse colon (arrows in Panels A and B), which were consistent with pneumatosis cystoides coli. One year before presentation, acute pain had developed in the left upper quadrant as a result of microperforation. At that time, CT revealed a small amount of air outside the colon and associated inflammation. The patient was treated nonoperatively, with good results. Given her persistent localized symptoms and the involvement of a discrete segment of her colon, laparoscopic resection of the transverse colon and splenic flexure was performed, without complications, and the patient has been asymptom-atic since the surgery. The pathological specimen showed the characteristic features of pneumatosis cystoides coli, air-filled cysts of various sizes in the submucosa and subserosa of the colon (Panel C, arrows). Pneumatosis cystoides coli can be focal or diffuse and occurs mainly in adults. It is usually asymptomatic but can cause obstruction or pneumoperitoneum as well as intermittent or persistent pain.

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“…Surgery is reserved for the rare patients with hemorrhage, obstruction, or perforation. Recently, oxygen administered by face mask to yield 70 75% oxygen and an arterial pO2 of 300 mm Hg [14,15] has been used effectively to decompress cysts in cases of severe PCI. By oxygen breathing, the balance of diffusion of gases between the cysts and venous blood is altered in favor of absorption of gases in the cyst, resulting in decompression.…”

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confidence: 99%

Pneumatosis intestinalis

Meyers

Ghahremani

Clements

et al. 1977

Gastrointest Radiol

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Pneumatosis intestinalis is a usually benign condition which may affect any segment of the gastrointestinal tract from the stomach to rectum. Occasionally, however, it may be a grave prognostic sign. This article presents the spectrum of diagnostic radiographic features of the entity with emphasis on differentiation of the underlying etiologic factors. Representative examples of pneumatosis intestinalis complicating various gastrointestinal disorders are illustrated.

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Treatment of Pneumatosis Cystoides Intestinalis With Oxygen

Cited by 34 publications

References 10 publications

High flow oxygen therapy for pneumatosis coli.

High flow oxygen therapy for pneumatosis coli.

Pneumatosis cystoides coli

Pneumatosis intestinalis

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